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The opioid tramadol is an effective analgesic for patients with clinically suspected acute appendicitis, according to the results of a prospective study presented at the 2015 Annual Meeting of the American College of Surgeons (ACS). “Tramadol…can provide significant reduction in abdominal pain and tenderness without altering the diagnostic confidence of the surgeon…in patients with suspected […]
Read MoreAuthors: Friedman BW et al. JAMA 2015 Oct 20. Neither cyclobenzaprine nor opioids are helpful as adjuncts to naproxen therapy for low back pain. Cyclobenzaprine (Flexeril) is a tricyclic antidepressant that is viewed as having “muscle relaxant” properties, even though it has no effect on motor neurons or skeletal muscle. Opioids act at the mu receptor […]
Read MoreAnesthesia & Analgesia: October 26, 2015 Tusman, Gerardo MD et al BACKGROUND: We sought to determine whether the response of pulmonary elimination of CO2 (VCO2) to a sudden increase in positive end-expiratory pressure (PEEP) could predict fluid responsiveness and serve as a noninvasive surrogate for cardiac index (CI). METHODS: Fifty-two patients undergoing cardiovascular surgery were […]
Read MoreAnesthesia & Analgesia: October 26, 2015 Brown, Rebecca BS et al BACKGROUND: It has been established that pain is frequently undertreated in children following outpatient surgery. Very few studies, however, have investigated this phenomenon in ethnically diverse populations. METHODS: This study included 105 families of children aged 2 to 15 years of Hispanic origin and […]
Read MoreAnesthesia & Analgesia: October 26, 2015 Miu Mihaela MD et al BACKGROUND: Surgical site infiltration with local anesthetic reduces analgesic requests in various types of surgeries. Because thyroid surgery may induce severe postoperative pain, we tested the hypothesis that ropivacaine surgical site infiltration would significantly decrease postoperative administration of morphine in patients undergoing thyroid surgery. […]
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