Anesthesia & Analgesia: February 2016 – Volume 122 – Issue 2 – p 503–508 AUTHORS: Mebel, Dmitry MD et al BACKGROUND: Compared with other procedures, complex skull base neurosurgery has the potential for increased intraoperative blood loss yet coagulation near eloquent cranial structures should be minimized. The safety and efficacy of the antifibrinolytic, tranexamic acid […]
Read MoreAnesthesia & Analgesia: February 2016 – Volume 122 – Issue 2 – p 449–453 AUTHORS: Lu, Zhen MPH et al BACKGROUND: Malignant hyperthermia (MH) is a rare yet potentially fatal pharmacogenetic disorder triggered by exposure to inhaled anesthetics and the depolarizing neuromuscular blocking drug succinylcholine. Epidemiologic research on MH is largely limited to inpatients. In […]
Read MoreThis is for our readers that practice pain management. Pharmacists in Indiana are three times more likely to refuse to dispense a controlled substance when they use the state prescription drug monitoring program than when they don’t, results from a new survey show. “The pharmacist is the last line of defense to check the red […]
Read MoreEur J Anaesthesiol. 2015 Nov;32(11):751-8. doi: 10.1097/EJA.0000000000000248. AUTHORS:Huynh TM et al BACKGROUND: Dexamethasone decreases postoperative pain and prolongs the duration of local anaesthetic peripheral nerve blocks in studies including a limited number of patients. OBJECTIVE: The objective of this study is to evaluate the effect of combining dexamethasone with local anaesthetic on sensory and motor peripheral […]
Read MoreEur J Anaesthesiol. 2015 Nov;32(11):759-63 AUTHORS: Szucs S et al BACKGROUND: Femoral neck fractures usually require operative fixation. Spinal anaesthesia is the preferred technique for many anaesthetists, although single-shot spinal anaesthesia may have severe haemodynamic side-effects. OBJECTIVE: To determine the initial minimum intrathecal dose of 0.5% isobaric bupivacaine required in order to achieve surgical anaesthesia within […]
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