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Uncategorized Published - 2 March, 2016    By - Dr Clemens
Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury

Crit Care Med. 2016 Jan AUTHORS: Welch TP et al OBJECTIVE: To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury. DESIGN: Retrospective cohort. SETTING: PICU in a university-affiliated children’s hospital level I trauma center. PATIENTS: Thirty-one children aged 0-18 years with severe traumatic […]

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Uncategorized Published - 2 March, 2016    By - Dr Clemens
A comparison between fentanyl plus celecoxib therapy and epidural anesthesia for postoperative pain management following laparoscopic gastrectomy

Surg Today. 2015 Dec 23 AUTHORS: Shibasaki S et al PURPOSE: To clarify the efficacy of postoperative pain management following laparoscopic gastrectomy (LG), we retrospectively compared pain assessments in patients who received fentanyl plus celecoxib with those who received epidural anesthesia. METHODS: From 2011 to 2012, 55 consecutive LG patients at our institution received 48 h of […]

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Uncategorized Published - 1 March, 2016    By - Dr Clemens
New Approach to Diagnosing Low Back Pain

Serum levels of the pro-inflammatory cytokine interleukin-6 (IL-6) vary in individuals with lumbar intervertebral disc disease and biochemical profiling of circulating cytokines may assist in refining personalised diagnoses of disc diseases, according to a study published in the journal Arthritis Research and Therapy. Low back pain is caused by multiple triggers that present in similar ways. […]

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Uncategorized Published - 1 March, 2016    By - Dr Clemens
Dry Eye Linked to Chronic Pain Syndromes

Researchers have found a link between dry eye and chronic pain syndromes — a finding that suggests that a new paradigm is needed for diagnosis and treatment to improve patient outcomes. “Our study indicates that some patients with dry eye have corneal somatosensory pathway dysfunction and would be better described as having neuropathic ocular pain,” […]

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Uncategorized Published - 1 March, 2016    By - Dr Clemens
Methylnaltrexone for Opioid-Induced Constipation Might Also Improve Overall Survival in Advanced Cancer Patients

Methylnaltrexone, a peripherally acting μ-opioid receptor (MOR) antagonist, may play a role in slowing tumor progression, new research has found. According to the study, methylnaltrexone influenced cancer progression and prolonged survival in patients with advanced cancer, suggesting that the MOR antagonist may be an important therapeutic target. “Our data suggest that methylnaltrexone used in advanced […]

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