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Eur J Anaesthesiol. 2016 Feb;33(2):90-5 AUTHORS: Ham SY et al BACKGROUND: Ondansetron, a 5-HT3 receptor antagonist, and aprepitant, a neurokinin-1 receptor antagonist, block the emetic effect of serotonin and neurokinin, respectively. Aprepitant combined with ondansetron can be more effective for preventing emesis in patients at high risk of postoperative nausea and vomiting (PONV). OBJECTIVE: To investigate […]
Read MoreJ Crit Care. 2016 Feb;31(1):31-5 AUTHORS: Rose L et al PURPOSE: The purpose was to describe characteristics and outcomes of restrained and nonrestrained patients enrolled in a randomized trial of protocolized sedation compared with protocolized sedation plus daily sedation interruption and to identify patient and treatment factors associated with physical restraint. METHODS: This was a post […]
Read MoreChildren who still have moderate to severe post-operative pain 1 month after a surgical procedure are at risk for deterioration of their health-related quality of life (HRQOL), according to a study published in the Journal of Pain. Severe post-surgical pain is common and can govern the stress response after surgery, which can result in delayed […]
Read MoreNewborns experience too much pain from routine medical procedures, especially premature infants with more intensive health needs, according to a policy statement by the American Academy of Pediatrics (AAP). Research suggests that repeated exposure to pain early in life can create changes in brain development and the body’s stress response systems that can last into […]
Read MorePatients in the PACU with a high risk for respiratory adverse events (RAEs) should be monitored for both noninvasive end-tidal carbon dioxide (CO2) and pulse oximetry using the Integrated Pulmonary Index (IPI), a new study suggests. RAEs can lead to increased duration in the PACU and greater medical costs, or a transfer to the ICU […]
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