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Uncategorized Published - 27 October, 2016    By - Dr Clemens
Influence of Mechanical Ventilation on the Incidence of Pneumothorax During Infraclavicular Subclavian Vein Catheterization: A Prospective Randomized Noninferiority Trial

Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 636–640 AUTHORS: Kim, Eugene MD et al BACKGROUND: It remains unclear whether we have to interrupt mechanical ventilation during infraclavicular subclavian venous catheterization. In practice, the clinicians’ choice about lung deflation depends on their own discretion. The purpose of this study was […]

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Uncategorized Published - 27 October, 2016    By - Dr Clemens
The Relationship Between Oxygen Reserve Index and Arterial Partial Pressure of Oxygen During Surgery

Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 626–633 AUTHORS: Applegate, Richard L. II MD et al BACKGROUND: The use of intraoperative pulse oximetry (SpO2) enhances hypoxia detection and is associated with fewer perioperative hypoxic events. However, SpO2 may be reported as 98% when arterial partial pressure of oxygen (PaO2) is […]

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Uncategorized Published - 27 October, 2016    By - Dr Clemens
Comparative Plasma and Cerebrospinal Fluid Pharmacokinetics of Paracetamol After Intravenous and Oral Administration

Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 610–615 AUTHORS: Langford, Roger A. BMBS, FRCA et al BACKGROUND: We compared plasma and cerebrospinal fluid (CSF) pharmacokinetics of paracetamol after intravenous (IV) and oral administration to determine dosing regimens that optimize CSF concentrations. METHODS: Twenty-one adult patients were assigned randomly to […]

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Uncategorized Published - 27 October, 2016    By - Dr Clemens
Practice and Outcomes of the Perioperative Surgical Home in a California Integrated Delivery System

Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 597–606 AUTHORS: Qiu, Chunyuan MD, MS et al BACKGROUND: In this article, we report on the implementation and impact of a Perioperative Surgical Home (PSH) model for the total knee arthroplasty at an integrated delivery system (Kaiser Permanente). METHODS: A multidisciplinary committee […]

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Uncategorized Published - 26 October, 2016    By - Dr Clemens
Lower Dose of Tranexamic Acid Favored for Arthroplasty Procedures

For the antifibrinolytic agent tranexamic acid, doses varying between 5 and 15 mg/kg failed to produce a dose-dependent drop in hemoglobin after total knee (TKA) or total hip arthroplasty (THA), leading study investigators to recommend using the lowest of these doses in orthopedic patients. “At my institution, we reviewed quite a bit of data while […]

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