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Uncategorized Published - 18 April, 2016    By - Dr Clemens
Lung Perfusion and Ventilation During Cardiopulmonary Bypass Reduces Early Structural Damage to Pulmonary Parenchyma

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 943–952 AUTHORS: Claudia Regina MD, PhD et al BACKGROUND: It is unclear whether maintaining pulmonary perfusion and ventilation during cardiopulmonary bypass (CPB) reduces pulmonary inflammatory tissue injury compared with standard CPB where the lungs are not ventilated and are minimally perfused. In […]

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Uncategorized Published - 18 April, 2016    By - Dr Clemens
Optimizing Thrombin Generation with 4-Factor Prothrombin Complex Concentrates in Neonatal Plasma After Cardiopulmonary Bypass

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 935–942 AUTHORS: Franklin, Sarah W. BA et al BACKGROUND: Bleeding is a serious complication after pediatric cardiopulmonary bypass (CPB) that is associated with an increase in perioperative morbidity and mortality. Four-factor prothrombin complex concentrates (4F-PCCs) have been used off-label to supplement transfusion […]

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Uncategorized Published - 15 April, 2016    By - Dr Clemens
Two Approaches to Lessen Need for Intubation

Authors: Spoletini G et al., JAMA 2016 Mar 15; High-flow oxygen and noninvasive positive pressure ventilation lowered reintubation rates in selected patient populations. During the past few years, interest has grown in using high-flow oxygen (HFO) and noninvasive positive pressure ventilation (NPPV) in lieu of intubation and mechanical ventilation (NEJM JW Gen Med Aug 1 […]

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Uncategorized Published - 15 April, 2016    By - Dr Clemens
A Comparison of the Haider Tube-Guard(R) Endotracheal Tube Holder Versus Adhesive Tape to Determine if This Novel Device Can Reduce Endotracheal Tube Movement and Prevent Unplanned Extubation.

Anesthesia & Analgesia: March 2016 AUTHORS: Buckley, Jack C. MD et al BACKGROUND: Endotracheal tube security is a critical safety issue. We compared the mobility of an in situ endotracheal tube secured with adhesive tape to the one secured with a new commercially available purpose-designed endotracheal tube-holder device (Haider Tube-Guard(R)). We also observed for the […]

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Uncategorized Published - 15 April, 2016    By - Dr Clemens
Prothrombin Complex Concentrates for Bleeding in the Perioperative Setting.

Anesthesia & Analgesia: March 2016 AUTHORS: Ghadimi, Kamrouz MD et al Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII. PCCs rapidly restore deficient coagulation factor concentrations to achieve hemostasis, but like with all […]

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