Anesthesia & Analgesia: May 2016 – Volume 122 – Issue 5 – p 1603–1613 AUTHORS: Glance, Laurent G. MD et al BACKGROUND: In creating the Merit-Based Incentive Payment System, Congress has mandated pay-for-performance (P4P) for all physicians, including anesthesiologists. There are currently no National Quality Forum–endorsed risk-adjusted outcome metrics for anesthesiologists to use as the […]
Read MoreAuthors: Eun-Ho Lee, M.D. et al Anesthesiology 5 2016, Vol.124, 1001-1011 Background: Hypoalbuminemia may increase the risk of acute kidney injury (AKI). The authors investigated whether the immediate preoperative administration of 20% albumin solution affects the incidence of AKI after off-pump coronary artery bypass surgery. Methods: In this prospective, single-center, randomized, parallel-arm double-blind trial, 220 patients with preoperative […]
Read MoreStudy finds fentanyl transdermal patches are too often prescribed to opioid-naïve and elderly patients, raising their risks of fatal adverse drug events. Interview with Caleb Alexander, MD Fentanyl patches are a highly potent options for cancer and non-cancer pain patients, but are contraindicated in opioid naïve patients. However, new research indicates that physicians may be […]
Read MoreAuthors: Andrew P. Wojtovich, Ph.D. et al Anesthesiology 5 2016, Vol.124, 1065-1076. Background: Anesthetic preconditioning (APC) is a clinically important phenomenon in which volatile anesthetics (VAs) protect tissues such as heart against ischemic injury. The mechanism of APC is thought to involve K+ channels encoded by the Slo gene family, and the authors showed previously that slo-2 is required for APC inCaenorhabditis […]
Read MoreEdited by Susan Sadoughi, MD, and André Sofair, MD, MPH Contrary to its marketing claims, OxyContin’s pain-relieving effects often fall short of 12 hours in many patients, which can lead to a host of other problems, according to an investigation by the Los Angeles Times. OxyContin is approved for 12-hour dosing. Several studies found that the drug’s effects […]
Read More