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Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 626–633 AUTHORS: Applegate, Richard L. II MD et al BACKGROUND: The use of intraoperative pulse oximetry (SpO2) enhances hypoxia detection and is associated with fewer perioperative hypoxic events. However, SpO2 may be reported as 98% when arterial partial pressure of oxygen (PaO2) is […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 610–615 AUTHORS: Langford, Roger A. BMBS, FRCA et al BACKGROUND: We compared plasma and cerebrospinal fluid (CSF) pharmacokinetics of paracetamol after intravenous (IV) and oral administration to determine dosing regimens that optimize CSF concentrations. METHODS: Twenty-one adult patients were assigned randomly to […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 597–606 AUTHORS: Qiu, Chunyuan MD, MS et al BACKGROUND: In this article, we report on the implementation and impact of a Perioperative Surgical Home (PSH) model for the total knee arthroplasty at an integrated delivery system (Kaiser Permanente). METHODS: A multidisciplinary committee […]
Read MoreFor the antifibrinolytic agent tranexamic acid, doses varying between 5 and 15 mg/kg failed to produce a dose-dependent drop in hemoglobin after total knee (TKA) or total hip arthroplasty (THA), leading study investigators to recommend using the lowest of these doses in orthopedic patients. “At my institution, we reviewed quite a bit of data while […]
Read MoreContinuing a series begun last year, we asked D. John Doyle, MD, PhD, a member of the Anesthesiology News advisory board, to pose 7 questions to an international airway management roundtable, whose members he picked. The responses, including those of Dr Doyle, follow. John Doyle, MD, PhD Chief of General Anesthesiology Anesthesiology Institute Cleveland Clinic […]
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