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Uncategorized Published - 11 November, 2016    By - Dr Clemens
Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension

Authors: Stefan Muenster, M.D. et al Published in Anesthesiology 11 2016, Vol.125, 952-963 Background: Transfusion of packed erythrocytes stored for a long duration is associated with increased pulmonary arterial pressure and vascular resistance. Prolonged storage decreases erythrocyte deformability, and older erythrocytes are rapidly removed from the circulation after transfusion. The authors studied whether treating stored packed ovine […]

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Uncategorized Published - 11 November, 2016    By - Dr Clemens
Blood Bupivacaine Concentrations After a Combined Single-Shot Sciatic Block and a Continuous Femoral Nerve Block in Pediatric Patients: A Prospective Observational Study.

Anesthesia & Analgesia: August 31, 2016 AUTHORS: Suresh, Santhanam MD et al BACKGROUND: We evaluated blood bupivacaine concentrations in children having a single-shot sciatic and continuous femoral blocks after anterior cruciate ligament repair. METHODS: Dried blood spot samples were analyzed for bupivacaine levels at 0, 5, 15, 30, 60, and 120 minutes and 4, 24, […]

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Uncategorized Published - 11 November, 2016    By - Dr Clemens
Subperception Stimulation May Provide Pain Relief For Some Spinal Cord Stimulation Patients

Patients with implanted devices for spinal cord stimulation (SCS) for whom paresthesia-based stimulation has failed to relieve pain may have an “effective alternative” in subperception stimulation at 1 kHz, a recent pilot study suggests. The investigators conducted a prospective, randomized study (Neuromodulation2016 May 17. [Epub ahead of print]) to apply the findings of a study […]

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Uncategorized Published - 11 November, 2016    By - Dr Clemens
Lower Dose of Tranexamic Acid Favored for Arthroplasty Procedures

For the antifibrinolytic agent tranexamic acid, doses varying between 5 and 15 mg/kg failed to produce a dose-dependent drop in hemoglobin after total knee (TKA) or total hip arthroplasty (THA), leading study investigators to recommend using the lowest of these doses in orthopedic patients. “At my institution, we reviewed quite a bit of data while […]

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Uncategorized Published - 10 November, 2016    By - Dr Clemens
Nasal Ventilation: Oxygenation, NO DESAT, and THRIVE

Anil Patel, MD, FRCA Consultant Anaesthetist Royal National Throat, Nose and Ear Hospital University College London Hospitals NHS Foundation Trust London, United Kingdom S.A. Reza Nouraei, MBBChir, PhD, FRCS Ear, Nose, and Throat Surgeon Honorary Senior Lecturer in Otolaryngology, University College London London, United Kingdom High-flow nasal oxygen optimizes preoxygenation and apnea time compared with […]

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