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Uncategorized Published - 12 July, 2016    By - Dr Clemens
A Multicenter, Randomized, Controlled Phase IIb Trial of Avoidance of Hyperoxemia during Cardiopulmonary Bypass

Authors: Shay P. McGuinness, M.B.Ch.B. et al Anesthesiology published on 7 2016 Background: Cardiac surgery utilizing cardiopulmonary bypass (CPB) is one of the most common forms of major surgery. Cardiac surgery–associated multiorgan dysfunction (CSA-MOD) is well recognized and includes acute kidney injury (AKI), hepatic impairment, myocardial damage, and postoperative neurologic deficit. Pathophysiology of CSA-MOD involves numerous injurious […]

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Uncategorized Published - 12 July, 2016    By - Dr Clemens
Neurodevelopmental Assessment in Kindergarten in Children Exposed to General Anesthesia before the Age of 4 Years: A Retrospective Matched Cohort Study

Authors: M. Ruth Graham, M.D., F.R.C.P.(C). et al     Anesthesiology published on 7 2016 Background: Animal studies demonstrate general anesthetic (GA) toxicity in the developing brain. Clinical reports raise concern, but the risk of GA exposure to neurodevelopment in children remains uncertain. Methods: The authors undertook a retrospective matched cohort study comparing children less than 4 yr of […]

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Uncategorized Published - 12 July, 2016    By - Dr Clemens
The perioperative surgical home: What’s in a name?

RONALD L. HARTER, MD | PHYSICIAN | JULY 7, 2016 A guest column by the American Society of Anesthesiologists, exclusive to KevinMD.com. Our institution, like countless others across the country, has been working to institute processes to achieve the “triple aim” of improving the quality of health care, increasing patient satisfaction, and reducing the cost of providing that care. As chair […]

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Uncategorized Published - 12 July, 2016    By - Dr Clemens
Does Pregabalin Cause Fetal Harm?

Authors: Pennell PB and Meador KJ., Neurology 2016 Jun 14; 86:2224 Prospective cohort study raises concern about teratogenic potential of this neuropsychiatric medication. Pregabalin is used on- and off-label for various neuropsychiatric conditions (e.g., seizure disorder, neuropathic pain, restless leg syndrome). Researchers sought to determine risk associated with pregabalin use during early pregnancy. A cohort of 683 […]

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Uncategorized Published - 12 July, 2016    By - Dr Clemens
Disseminated Intravascular Coagulation: A Practical Approach

Authors: Jecko Thachil, M.D., M.R.C.P., F.R.C.Path. Anesthesiology 7 2016, Vol.125, 230-236. Anesthesiologists may encounter patients with disseminated intravascular coagulation, a potential complication of severe sepsis or major trauma. This practical guide discusses the clinical approach, laboratory diagnosis, and current management of this condition. The Clinical Scenario A 46-yr-old woman is admitted to the critical care unit […]

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