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Researchers from the Technical University of Munich (TUM) claim to have discovered the molecular mechanism for the sedative thalidomide (Thalomid, Celgene). The findings could help to improve cancer treatment Nat Med. 2016 Jun 13. Thalidomide, an immunomodulatory drug developed in West Germany during the 1950s, was marketed in Europe as the first safe sleeping pill—even […]
Read MoreThe implementation of a multimodal analgesic protocol may be a simple, effective way to boost the documentation of preoperative pain scores and opioid use in an acute pain service, new research suggests. Multimodal protocols for nonopioid analgesia using acetaminophen, cyclooxygenase-2 inhibitors, gabapentinoids and peripheral nerve catheters have been shown to decrease opioid use and improve […]
Read MoreA hernia repair patient suffered from internal bleeding in PACU for more than 2 hours before undergoing emergency surgery. An anesthesiologist is liable for the death of a woman who bled out in PACU after undergoing a hernia repair, an Illinois appellate court recently ruled, leaving the doctor’s anesthesia group on the hook for a multi-million dollar […]
Read MoreThe most recent data on obstetric lacerations during vaginal delivery have been incorporated into recommendations from the American College of Obstetricians and Gynecologists (ACOG), published in the July issue of Obstetrics & Gynecology. However, guidance on prevention and repair of severe perineal lacerations and on indications for episiotomy remains largely hampered by insufficient evidence. An estimated 53% to […]
Read MoreLevels of the inflammatory marker C-reactive protein (CRP) are significantly elevated in young adults with migraine, which may not only offer insights into the pathogenesis of the condition but also point to novel therapeutic avenues, researchers say. Delegates here at the American Headache Society (AHS) 58th Annual Scientific Meeting heard that levels of the protein, […]
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