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AUTHORS: Sauer, Reine-Solange PhD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 675–685 BACKGROUND: Inhibitors of cyclooxygenase, which block the formation of prostaglandin (PG) E2, are the standard treatment of inflammatory pain. These drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects that limit their clinical use. Cyclodextrins […]
Read MoreSeronegative rheumatoid arthritis (RA) is strongly associated with fibromyalgia, according to a newly published study. However, one expert suggests the difference seen between seronegative vs seropositive RA and fibromyalgia might reflect the greater scrutiny of patients with seronegative RA in typical clinical practice. Jayanth Doss, MD, from the Division of Rheumatology and Immunology, Duke University, […]
Read MoreRoutine physical exercise is an important factor in managing widespread musculoskeletal pain in conditions such as fibromyalgia (FM), but patients may fear that such exertion will worsen pain. Now, results of a pilot study suggest that a combination of cognitive behavioral therapy (CBT) that emphasizes pain coping strategies and a specially tailored exercise program reduces […]
Read MoreOnly a minority of patients with moderate to severe fibromyalgia get pain relief from the antiepileptic pregabalin, but the quality of that pain relief is strong, an updated review of the related literature concludes. “Pregabalin works extraordinarily well in 1 person in 10 who has fibromyalgia and it doesn’t work for the other 9 patients, […]
Read MoreHello. I am Dr Jonathan Kay, the Timothy S. and Elaine L. Peterson Chair in Rheumatology, and professor of medicine at the University of Massachusetts Medical School. Welcome to my Medscape blog. Fibromyalgia is a label that is a challenge for primary care physicians and other physicians alike. Patients present with generalized pain, fatigue, and […]
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