Authors: Lamy A et al., N Engl J Med 2016 Oct 23; Data on outcomes, cost, and quality of life did not differ significantly between the two coronary artery bypass grafting strategies. In the multinational, randomized CORONARY trial, comparing off-pump (beating heart) with on-pump coronary artery bypass grafting (CABG), the primary endpoint did not differ significantly between […]
Read MoreEuropean Journal of Anaesthesiology: April 2016 – Volume 33 – Issue 4 – p 275–282 AUTHORS: Lee, Su Hyun et al BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a risk factor that increases the incidence of postoperative cardiopulmonary morbidity and mortality after lung resection. Dexmedetomidine, a selective α2-adrenoreceptor agonist, has been reported previously to attenuate intrapulmonary […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 626–633 AUTHORS: Applegate, Richard L. II MD et al BACKGROUND: The use of intraoperative pulse oximetry (SpO2) enhances hypoxia detection and is associated with fewer perioperative hypoxic events. However, SpO2 may be reported as 98% when arterial partial pressure of oxygen (PaO2) is […]
Read MoreAuthors: Pavel S. Roshanov, M.D., M.Sc. et al Anesthesiology published on October 23, 2016. Background: The effect on cardiovascular outcomes of withholding angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac surgery is unknown. Methods: In this international prospective cohort study, the authors analyzed data from 14,687 patients (including 4,802 angiotensin-converting enzyme inhibitor/angiotensin II […]
Read MoreAuthors: Patrick J. McCormick, M.D. et al Anesthesiology published on October 23, 2016. Background: We tested the hypothesis that an electronic alert for a “double low” of mean arterial pressure less than 75 mmHg and a bispectral index less than 45 reduces the primary outcome of 90-day mortality. Methods: Adults having noncardiac surgery were randomized to receive either […]
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