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Uncategorized Published - 2 November, 2016    By - Dr Clemens
Low Tidal Volume Ventilation With Low PEEP During Surgery May Induce Lung Inflammation

Authors: Hitoshi Sato et al BMC Anesthesiol. 2016;16(47) Background: Compared to conventional tidal volume ventilation, low tidal-volume ventilation reduces mortality in cased of acute respiratory distress syndrome. The aim of the present study is to determine whether low tidal-volume ventilation reduces the production of inflammatory mediators in the lungs and improves physiological status during hepatic […]

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Uncategorized Published - 2 November, 2016    By - Dr Clemens
IV Treatment of Centralized Pain and Headache

Learn more about the use of subanesthetic dosages of IV agents in an outpatient headache and chronic pain clinic. By John Claude Krusz, PhD, MD Most pain practitioners now believe that neuroinflammation plays a role in the initiation, maintenance, and exacerbation of the chronic pain process in the nervous system—both centrally and peripherally.1 Microglial cell activation in […]

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Uncategorized Published - 2 November, 2016    By - Dr Clemens
Minimum Effective Doses of Succinylcholine and Rocuronium During Electroconvulsive Therapy: A Prospective, Randomized, Crossover Trial

Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 587–596 AUTHORS: Mirzakhani, Hooman MD, PhD et al BACKGROUND: Neuromuscular blockade is required to control excessive muscle contractions during electroconvulsive therapy (ECT). In a crossover, assessor-blinded, prospective randomized study, we studied the minimum effective dose (MED) of succinylcholine and rocuronium for ECT. […]

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Uncategorized Published - 2 November, 2016    By - Dr Clemens
Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients

Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 570–577 AUTHORS: Fabbro, Michael II DO et al BACKGROUND: The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia […]

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Uncategorized Published - 2 November, 2016    By - Dr Clemens
Preoperative Frailty Tests Predict Long-Term Outcomes in Seniors

Preoperative frailty assessments may help predict mortality and functional decline among seniors undergoing cardiac surgical procedures. The results of this systematic review were published online August 23 in the Annals of Internal Medicine. “Despite various ways of measuring frailty, we found strong evidence that it predicts mortality at 6 months or later after major or minimally invasive procedures,” […]

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