Anesthesia & Analgesia: September 2016 AUTHORS: Choi, Eun Kyung MD, PhD et al BACKGROUND: Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrinato iron (III) (FeTMPyP) by selective […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1471–1479 AUTHORS: Belcher, Allan W. DO et al BACKGROUND: Opioids can contribute to postoperative desaturation. Short-acting opioids, titrated to need, may cause less desaturation than longer-acting opioids. We thus tested the primary hypothesis that long-acting patient-controlled intravenous opioids are associated with more […]
Read MoreAuthors: Vincent J. Alentado, BS et al Spine. 2016;41(14):1167-1172. Study Design. Retrospective Review. Objective. The aim of this study was to determine medical, radiographic, and surgical risk factors for the development of adjacent segment disease (ASD) after lumbar fusion. Summary of Background Data. ASD is a recognized outcome of spinal fusion that leads to increased costs and debilitating symptoms […]
Read MoreAnesthesia & Analgesia: November 2016 – Volume 123 – Issue 5 – p 1297–1301 AUTHORS: Dexter, Franklin MD, PhD et al BACKGROUND: In order to provide guidance to organizations considering elective weekend surgical case scheduling, we analyzed data from the American Society of Anesthesiologist’s Anesthesia Quality Institute. We determined the US anesthesia workload on Saturdays […]
Read MoreAuthors: Abdul Basit et al BMJ Open Diabetes Res Care. 2016;4(1) Objective: To assess the effect of high-dose vitamin D in patients with painful diabetic neuropathy. Methods: A single intramuscular dose of 600 000 IU vitamin D was administered, and the effects on metabolic parameters and neuropathic pain assessed over 20 weeks. Results: 143 participants with predominantly type 2 diabetes, […]
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