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Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 925–932 AUTHORS: Nishimura, Akiko DDS, PhD et al BACKGROUND: The revised Starling law suggests that intravenously infused fluid may leak into the interstitium and not remain in the intravascular space. This hypothesis is supported by clinical findings that postoperative weight gain is […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 903–909 AUTHORS: Faust, Andrew C. PharmD, BCPS et al BACKGROUND: Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a “lighter” depth of sedation. Among these strategies are “analgosedation” protocols, which […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 885–893 AUTHORS: Zaouter, Cedrick MD, MSc et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 869–876 AUTHORS: Sawada, Atsushi MD, PhD et al BACKGROUND: A harmful effect of stress hormone secretion during surgery is lipolysis and proteolysis to maintain normal blood glucose levels. A well-titrated general anesthetic improves blood glucose control by suppressing secretion of these stress […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 910–924 AUTHORS: Winearls, James BSc, MBBS, MRCP, FCICM et al Hemorrhage in the setting of severe trauma is a leading cause of death worldwide. The pathophysiology of hemorrhage and coagulopathy in severe trauma is complex and remains poorly understood. Most clinicians currently […]
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