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Uncategorized Published - 20 June, 2017    By - Dr Clemens
To Stop or Not, That Is the Question: Acute Pain Management for the Patient on Chronic Buprenorphine

Authors: T. Anthony Anderson, Ph.D., M.D. et al Anesthesiology 6 2017, Vol.126, 1180-1186. The management of acute perioperative pain in patients on chronic buprenorphine as opioid maintenance therapy is a complex process. We describe pain management approaches for patients on buprenorphine who present for elective and urgent/emergent surgery. Background Opioid use disorder, a chronic neurobehavioral disease, […]

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Uncategorized Published - 20 June, 2017    By - Dr Clemens
Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery: A Randomized Controlled Trial

Authors: Juan C. Gómez-Izquierdo, M.D. et al Anesthesiology 7 2017, Vol.127, 36-49. Background: Inadequate perioperative fluid therapy impairs gastrointestinal function. Studies primarily evaluating the impact of goal-directed fluid therapy on primary postoperative ileus are missing. The objective of this study was to determine whether goal-directed fluid therapy reduces the incidence of primary postoperative ileus after laparoscopic colorectal […]

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Uncategorized Published - 19 June, 2017    By - Dr Clemens
Management of Severe Bleeding in Patients Treated with Direct Oral Anticoagulants: An Observational Registry Analysis

Authors: Pierre Albaladejo, M.D., Ph.D. et al Anesthesiology 7 2017, Vol.127, 111-120. Background: The use of prothrombin complex concentrates and the role of plasma concentration of anticoagulants in the management of bleeding in patients treated with direct oral anticoagulants are still debated. Our aim was to describe management strategies and outcomes of severe bleeding events in patients […]

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Uncategorized Published - 19 June, 2017    By - Dr Clemens
A Systematic Review and Meta-analysis Examining the Impact of Incident Postoperative Delirium on Mortality

Authors: Gavin M. Hamilton, M.D., M.Sc. et al Anesthesiology 7 2017, Vol.127, 78-88. Background: Delirium is an acute and reversible geriatric syndrome that represents a decompensation of cerebral function. Delirium is associated with adverse postoperative outcomes, but controversy exists regarding whether delirium is an independent predictor of mortality. Thus, we assessed the association between incident postoperative delirium […]

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Uncategorized Published - 19 June, 2017    By - Dr Clemens
Epidural Neostigmine versusFentanyl to Decrease Bupivacaine Use in Patient-controlled Epidural Analgesia during Labor: A Randomized, Double-blind, Controlled Study

Authors: Jessica L. Booth, M.D. et al Anesthesiology 7 2017, Vol.127, 50-57. Background: The addition of opioids to epidural local anesthetic reduces local anesthetic consumption by 20% but at the expense of side effects and time spent for regulatory compliance paperwork. Epidural neostigmine also reduces local anesthetic use. The authors hypothesized that epidural bupivacaine with neostigmine would […]

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