Authors: Karim Asehnoune, M.D., Ph.D. et al Anesthesiology published on June 22, 2017 Background: Patients with brain injury are at high risk of extubation failure. Methods: We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in […]
Read MoreA weekly injectable depot formulation of buprenorphine may be effective in treating opioid use disorder, according to a small, industry-funded, phase II trial published in JAMA Psychiatry. Currently, sublingual buprenorphine can be diverted and misused. Fifty patients with opioid use disorder who weren’t seeking treatment were randomized to receive two 24- or 32-mg doses of injectable […]
Read MoreAUTHORS: Hoftman, Nir MD et al Anesthesia & Analgesia: March 8, 2017 BACKGROUND: Tidal volume selection during mechanical ventilation utilizes dogmatic formulas that only consider a patient’s predicted body weight (PBW). In this study, we investigate whether forced vital capacity (FVC) (1) correlates better to total lung capacity (TLC) than PBW, (2) predicts low pulmonary compliance, […]
Read MoreAUTHORS: Butwick, Alexander J. MBBS, FRCA, MS et al Anesthesia & Analgesia: March 8, 2017 BACKGROUND: Women who undergo intrapartum caesarean delivery (CD) are at increased risk of postpartum hemorrhage (PPH) compared with those undergoing prelabor CD. To determine whether the presence and strength of the associations between individual risk factors and severe PPH vary among […]
Read MoreDespite becoming a widespread practice, routine use of video laryngoscopy in the ICU is not supported by the evidence. This is the argument made in a recent editorial in JAMA, titled “Video Laryngoscopy in the Intensive Care Unit: Seeing Is Believing, but That Does Not Mean It’s True.” The editorial, by Brian O’Gara, MD, et al (JAMA 2017 […]
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