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Uncategorized Published - 11 September, 2017    By - Dr Clemens
Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Posterior Spinal Fusion Surgery: A Randomized, Double-Blinded, Controlled Trial

Anesthesiology · April 24, 2017 BACKGROUND Patients undergoing spinal fusion surgery often experience severe pain during the first three postoperative days. The aim of this parallel-group randomized trial was to assess the effect of the long-duration opioid methadone on postoperative analgesic requirements, pain scores, and patient satisfaction after complex spine surgery. METHODS One hundred twenty patients were […]

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Uncategorized Published - 11 September, 2017    By - Dr Clemens
Dexamethasone Versus Standard Treatment for Postoperative Nausea and Vomiting in Gastrointestinal Surgery: Randomised Controlled Trial (DREAMS Trial)

BMJ · April 18, 2017 Objectives To determine whether preoperative dexamethasone reduces postoperative vomiting in patients undergoing elective bowel surgery and whether it is associated with other measurable benefits during recovery from surgery, including quicker return to oral diet and reduced length of stay. Design Pragmatic two arm parallel group randomised trial with blinded postoperative care and outcome assessment. […]

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Uncategorized Published - 8 September, 2017    By - Dr Clemens
Tetrodotoxin, Epinephrine, and Chemical Permeation Enhancer Combinations in Peripheral Nerve Blockade

AUTHORS: Santamaria, Claudia M. MD et al Anesthesia & Analgesia: June 2017 – Volume 124 – Issue 6 – p 1804–1812 BACKGROUND: Chemical permeation enhancers (CPEs) have the potential to improve nerve blockade by site 1 sodium channel blockers such as tetrodotoxin (TTX). Here, we investigated the efficacy and toxicity of CPE-enhanced nerve blockade across a […]

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Uncategorized Published - 8 September, 2017    By - Dr Clemens
Optimizing Anesthesia-Related Waste Disposal in the Operating Room: A Brief Report.

AUTHORS: Hubbard, Richard M. MD et al Anesthesia & Analgesia: April 21, 2017 Misappropriation of noncontaminated waste into regulated medical waste (RMW) containers is a source of added expense to health care facilities. The operating room is a significant contributor to RMW waste production. This study sought to determine whether disposing of anesthesia-related waste in standard […]

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Uncategorized Published - 8 September, 2017    By - Dr Clemens
A Prospective, Randomized, Clinical Trial on the Effects of a Valveless Trocar on Respiratory Mechanics During Robotic Radical Cystectomy: A Pilot Study

AUTHORS: Covotta, Marco MD et al Anesthesia & Analgesia: June 2017 – Volume 124 – Issue 6 – p 1794–1801 BACKGROUND: Prolonged pneumoperitoneum and Trendelenburg positioning for robot-assisted radical cystectomy (RARC) are essential for optimizing visualization of the operative field, although they worsen hemodynamic and respiratory function. Our hypothesis is that the use of a valveless […]

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