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Uncategorized Published - 28 February, 2017    By - Dr Clemens
Intraabdominal Surgery and Anesthesia Management

Author: John Hedley-Whyte, M.D., F.A.C.P., F.R.C.A., M.R.C.S. Anesthesiology 3 2017, Vol.126, 543-546. Inspired Oxygenation in Surgical Patients During General Anesthesia With Controlled Ventilation: A Concept of Atelectasis. By Bendixen HH, Hedley-Whyte J, and Laver MB. New Engl J Med 1963; 269:991–996. Reprinted with permission. Abstract: The purpose of this study was to determine if the pattern of […]

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Uncategorized Published - 28 February, 2017    By - Dr Clemens
Influence of Ethanol on Oxycodone-induced Respiratory Depression: A Dose-escalating Study in Young and Elderly Individuals

Authors: Rutger van der Schrier, M.D. et al Anesthesiology 3 2017, Vol.126, 534-542. Background: Respiratory depression is a potentially fatal complication of opioid use, which may be exacerbated by simultaneous ethanol intake. In this three-way sequential crossover dose-escalating study, the influence of coadministration of oral oxycodone and intravenous ethanol was assessed on resting ventilation, apneic events and […]

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Uncategorized Published - 28 February, 2017    By - Dr Clemens
Comparison of the Prognostic Significance of Initial Blood Lactate and Base Deficit in Trauma Patients

Authors: Mathieu Raux, M.D., Ph.D. et al Anesthesiology 3 2017, Vol.126, 522-533. Background: Initial blood lactate and base deficit have been shown to be prognostic biomarkers in trauma, but their respective performances have not been compared. Methods: Blood lactate levels and base deficit were measured at admission in trauma patients in three level 1 trauma centers. This was […]

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Uncategorized Published - 28 February, 2017    By - Dr Clemens
A Perioperative Systems Design to Improve Intraoperative Glucose Monitoring Is Associated with a Reduction in Surgical Site Infections in a Diabetic Patient Population

Authors: Jesse M. Ehrenfeld, M.D., M.P.H. et al Anesthesiology 3 2017, Vol.126, 431-440. Background: Diabetic patients receiving insulin should have periodic intraoperative glucose measurement. The authors conducted a care redesign effort to improve intraoperative glucose monitoring. Methods: With approval from Vanderbilt University Human Research Protection Program (Nashville, Tennessee), the authors created an automatic system to identify diabetic patients, […]

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Uncategorized Published - 28 February, 2017    By - Dr Clemens
Dexmedetomidine Disrupts the Local and Global Efficiencies of Large-scale Brain Networks

Authors: Javeria A. Hashmi, Ph.D. et al Anesthesiology 3 2017, Vol.126, 419-430. Background: A clear understanding of the neural basis of consciousness is fundamental to research in clinical and basic neuroscience disciplines and anesthesia. Recently, decreased efficiency of information integration was suggested as a core network feature of propofol-induced unconsciousness. However, it is unclear whether this finding […]

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