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Authors: Jacqueline M. Leung, M.D., M.P.H. et al Anesthesiology 10 2017, Vol.127, 633-644. Background: Postoperative pain and opioid use are associated with postoperative delirium. We designed a single-center, randomized, placebo-controlled, parallel-arm, double-blinded trial to determine whether perioperative administration of gabapentin reduced postoperative delirium after noncardiac surgery. Methods: Patients were randomly assigned to receive placebo (N = 347) or […]
Read MoreThe observations of Karen Sullivan Sibert, MD a Los Angeles anesthesiologist The longer you practice a profession, the easier it is not to bother to learn the next new thing. We may think we’re doing just fine without that new drug, or that new piece of expensive equipment. We’ve seen how the new drug sometimes turns out […]
Read MoreAuthors: May Hua, M.D. et al Anesthesiology published on September 14, 2017. Background: Recent reports have raised concerns that public reporting of 30-day mortality after cardiac surgery may delay decisions to withdraw life-sustaining therapies for some patients. The authors sought to examine whether timing of mortality after coronary artery bypass graft surgery significantly increases after day 30 […]
Read MoreAuthors: Min-Ching Kuo, Ph.D. et al Anesthesiology published on September 14, 2017. Background: Previous studies showed that synaptic transmission is affected by general anesthetics, but an anesthetic dose response in freely moving animals has not been done. The hippocampus provides a neural network for the evaluation of isoflurane and pentobarbital on multisynaptic transmission that is relevant to […]
Read MoreRetrospective data suggest that a higher SINS score is associated with radiotherapy failure. Complete pain response to spinal radiotherapy is associated with a Spinal Instability Neoplastic Score (SINS) of 7 or lower, according to a study published in The Oncologist.1 Retrospective data suggest that a higher SINS score is associated with radiotherapy failure. This study aimed […]
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