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AUTHORS: Delaney, Meghan DO, MPH et al Anesthesia & Analgesia: June 2017 – Volume 124 – Issue 6 – p 1777–1782 BACKGROUND: Cardiac surgery is the most common setting for massive transfusion in medically advanced countries. Studies of massive transfusion after injury suggest that the ratios of administered plasma and platelets (PLT) to red blood cells […]
Read MoreAUTHORS: Kubota, Kenta MD et al Anesthesia & Analgesia: June 2017 – Volume 124 – Issue 6 – p 1771–1776 BACKGROUND: Acute kidney injury (AKI) often occurs after cardiac surgery. During cardiac surgery, plasma free hemoglobin (fHb) would increase due to hemolysis. Since plasma fHb is thought to be nephrotoxic, haptoglobin, which is an fHb scavenger, […]
Read MorePostoperative use of opioid analgesics increases the risk of respiratory depression, which can lead to brain damage or death. Perioperative lidocaine does not reduce morphine use in the first 24 hours after posterior spinal arthrodesis and offers no measurable benefits, according to a randomized placebo-controlled trial recently published in Pain.1 Postoperative use of opioid analgesics increases the risk […]
Read MoreAuthors: Jessica L. Booth, M.D. et al Anesthesiology 7 2017, Vol.127, 50-57. Background: The addition of opioids to epidural local anesthetic reduces local anesthetic consumption by 20% but at the expense of side effects and time spent for regulatory compliance paperwork. Epidural neostigmine also reduces local anesthetic use. The authors hypothesized that epidural bupivacaine with neostigmine would […]
Read MoreAUTHORS: Lee, Alex T. MD et al Anesthesia & Analgesia: August 2017 – Volume 125 – Issue 2 – p 514–520 BACKGROUND: Antiplatelet medications are usually discontinued before elective neurosurgery, but this is not an option for emergent neurosurgery. We performed a retrospective cohort study to examine whether preoperative aspirin use was associated with worse outcomes […]
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