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Author: Paul E.MarikMD, FCCP et al Background The global burden of sepsis is estimated as 15 to 19 million cases annually, with a mortality rate approaching 60% in low-income countries. Methods In this retrospective before-after clinical study, we compared the outcome and clinical course of consecutive septic patients treated with intravenous vitamin C, hydrocortisone, and thiamine during […]
Read MoreAuthors: László Asztalos, M.D. et al Anesthesiology 9 2017, Vol.127, 441-449. Background: Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg. We investigated whether these doses of sugammadex can also reverse vecuronium at a similar level of block. Methods: Sixty-five patients were randomly assigned, and 64 were […]
Read MoreBy SEAN FOX MD Respiratory illness, sepsis, and trauma are three important entities afflicting children that may lead to needing to manage a child’s airway. Airway management in the ED is a complex interplay of patient factors, clinical illness status, and provider factors that, through our thorough training we become proficient at navigating. We have discussed many airway concepts previously (ex, ETT Depth, Cuffed ETTs, Apneic […]
Read MoreAuthors: Min-Ching Kuo, Ph.D. et al Anesthesiology 11 2017, Vol.127, 838-851. Background: Previous studies showed that synaptic transmission is affected by general anesthetics, but an anesthetic dose response in freely moving animals has not been done. The hippocampus provides a neural network for the evaluation of isoflurane and pentobarbital on multisynaptic transmission that is relevant to memory […]
Read MoreThe Heart of the Matter: Finding Meaning in Medicine and Discovering How Compassionate Doctors Can Save Physicians are expected to improve or save the lives of their patients, yet a growing number of physicians are struggling to enhance their own lives. It is estimated that 400 U.S. physicians a year commit suicide and thousands of others struggle […]
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