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Anesthesiology Published - 4 September, 2025    By - Dr Clemens
Isoflurane Exposure Influence on Sleep Architecture in a Rat Model of Alzheimer’s Disease

Author: Kreuzer M, et al. Anesthesia & Analgesia, August 29, 2025. doi:10.1213/ANE.0000000000007717 This experimental study investigated the effects of isoflurane anesthesia on sleep and recovery patterns in a rat model of Alzheimer’s disease (TgF344-AD). The researchers used EEG and EMG recordings in 8 transgenic rats and 7 age-matched controls to monitor WAKE, NREM, and REM […]

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Anesthesiology Published - 4 September, 2025    By - Dr Clemens
Dexmedetomidine Combined With Lidocaine Laryngopharyngeal Spray Reduces Coughing During Extubation in Female Patients Undergoing Thyroidectomy

Author: Zhao D, et al. Anesthesia & Analgesia, August 19, 2025. doi:10.1213/ANE.0000000000007725 This letter to the editor comments on a recent randomized clinical trial by Wang et al. that investigated dexmedetomidine combined with lidocaine laryngopharyngeal spray for reducing coughing during extubation in thyroidectomy patients. The authors acknowledge the study’s contribution but raise two key concerns. […]

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Anesthesiology Published - 4 September, 2025    By - Dr Clemens
Magnesium sulfate and sugammadex: implications for routine practice

Author: Fuchs-Buder T, et al. Current Opinion in Anesthesiology 38(4):349-352, August 2025. doi:10.1097/ACO.0000000000001507 This review discusses the interaction between magnesium sulfate (MgSO₄) and neuromuscular blockade, as well as the implications for reversal with sugammadex. Magnesium enhances neuromuscular blockade by accelerating onset, prolonging duration, and delaying recovery. Administering MgSO₄ soon after recovery may even trigger recurrence […]

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Anesthesiology Published - 4 September, 2025    By - Dr Clemens
5 important CRNA updates for ASC leaders

Author: Cameron Cortigiano Becker’s ASC Review Here are five updates on CRNAs for industry leaders to know, as reported by Becker’s since June 3: More than 40% of CRNAs support updating discharge policies to allow patients post-anesthesia to leave with rideshare services if accompanied by an adult, according to a report from Georgia Public Broadcasting.  UnitedHealthcare issued a policy update […]

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Anesthesiology Published - 4 September, 2025    By - Dr Clemens
Xenon and Argon as Neuroprotective Treatments for Perinatal Hypoxic-Ischemic Brain Injury

Author: Barros M, et al. Anesthesia & Analgesia 141(2):327-342, August 2025. doi:10.1213/ANE.0000000000007223 This preclinical systematic review and meta-analysis compared xenon and argon as neuroprotective treatments in animal models of perinatal hypoxic-ischemic encephalopathy (HIE). Twenty-one studies (data from 1591 animals across mice, rats, and piglets) met inclusion criteria. Using random-effects pairwise meta-analyses, both gases significantly improved […]

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