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Authors: Johanna M. Lee, A.B. et al Anesthesiology published on June 29, 2017. Background: In adults, frontal electroencephalogram patterns observed during propofol-induced unconsciousness consist of slow oscillations (0.1 to 1 Hz) and coherent alpha oscillations (8 to 13 Hz). Given that the nervous system undergoes significant changes during development, anesthesia-induced electroencephalogram oscillations in children may differ from […]
Read MoreCurrent recommendations for outcome measures in clinical trials for chronic pain were outlined. Standardized and clinically meaningful outcome measures in clinical trials in chronic pain may enhance efforts to develop effective treatments for chronic pain patients. Diane Flynn, MD, MPH, from Madigan Army Medical Center, outlined the current recommendations for outcome measures in clinical trials […]
Read MoreAuthors: Adler NE and Glymour M., JAMA Intern Med 2017 Jun 12; More than half of adults who didn’t complete high school had adverse CV events during their lifetimes. Educational attainment is associated with risk for cardiovascular disease (CVD), presumably as a marker or mediator of other traditional risk factors. To clarify the magnitude of this risk, […]
Read MoreAuthors: WJ., J Am Coll Cardiol 2017 May 16; 69:2393 A high rate of adverse events prompts the question of whether earlier intervention would improve outcomes. The authors of this international, four-site study examined longitudinal outcomes data on 305 patients (mean age, 73; 75% men) who were identified on baseline echocardiograms with moderate aortic stenosis (AS; defined […]
Read MoreAuthors: Edmond C. K. Li, M.D. et al Anesthesiology 7 2017, Vol.127, 204-205. To the Editor: We read the secondary analysis of the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II (ENIGMA II) trial for severe postoperative nausea and vomiting (PONV) with great interest.1 Because PONV remains an often-cited risk in using nitrous oxide,2 the […]
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