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Serotonin affects the part of the brain involved in drug reward and cue reactivity, particularly through the serotonin 2C receptors. A recent study published in ACS Chemical Neuroscience reported that a prescription weight-loss drug reduced the urge to use opiates like oxycodone.1 Current treatments to reduce opiate misuse operate by occupying opioid receptors in the brain to […]
Read MoreA single glucocorticoid intradiscal injection (GC IDI) provided relief from low back pain (LBP) at 1, but not 12, months in patients with active discopathy, as indicated by a study recently published in the Annals of Internal Medicine.1 Some patients with chronic LBP exhibit intervertebral disc changes on magnetic resonance imaging (MRI), which are categorized according […]
Read MoreAny questions regarding the safety of tranexamic acid in patients undergoing cardiac surgery seem to have been put to rest with the ATACAS (Aspirin and Tranexamic Acid For Coronary Artery Surgery) trial. In a cohort of nearly 5,000 patients, the trial concluded that tranexamic acid was associated with a lower risk for bleeding than placebo, […]
Read MoreAlthough dexamethasone may be a beneficial adjunct to surgery in terms of its antiemetic and anti-inflammatory effects, a team of researchers from Thomas Jefferson University Hospital has found that it may have a darker side, particularly in diabetic patients. A pilot study concluded that dexamethasone administration was associated with significant postoperative hyperglycemia in these patients […]
Read MoreUnderbody warming blankets ultimately may prove to be a better choice than their overbody counterparts, with respect to both treating and preventing hypothermia, according to a recent study. “A few years have passed since underbody-type blankets were introduced to the market,” began Hiroshi Sumida, MD, a staf f anesthesiologist at the Tohoku University School of […]
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