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Uncategorized Published - 10 August, 2017    By - Dr Clemens
Left Lateral Table Tilt for Elective Cesarean Delivery under Spinal Anesthesia Has No Effect on Neonatal Acid–Base Status: A Randomized Controlled Trial

Authors: Allison J. Lee, M.D. et al Anesthesiology 8 2017, Vol.127, 241-249. Background: Current recommendations for women undergoing cesarean delivery include 15° left tilt for uterine displacement to prevent aortocaval compression, although this degree of tilt is practically never achieved. We hypothesized that under contemporary clinical practice, including a crystalloid coload and phenylephrine infusion targeted at maintaining […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
A Prospective Study of Age-dependent Changes in Propofol-induced Electroencephalogram Oscillations in Children

Authors: Johanna M. Lee, A.B. et al Anesthesiology 8 2017, Vol.127, 293-306. Background: In adults, frontal electroencephalogram patterns observed during propofol-induced unconsciousness consist of slow oscillations (0.1 to 1 Hz) and coherent alpha oscillations (8 to 13 Hz). Given that the nervous system undergoes significant changes during development, anesthesia-induced electroencephalogram oscillations in children may differ from those […]

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Uncategorized Published - 10 August, 2017    By - Dr Clemens
Pupillometry-guided Intraoperative Remifentanil Administration versus Standard Practice Influences Opioid Use: A Randomized Study

Authors: Nada Sabourdin, M.D. et al Anesthesiology 8 2017, Vol.127, 284-292. Background: Pupillometry has shown promising results for assessing nociception in anesthetized patients. However, its benefits in clinical practice are not demonstrated. The aim of this prospective randomized study was to evaluate the impact of intraoperative pupillometry monitoring on perioperative opioid consumption in major gynecologic surgery. Methods: After […]

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Uncategorized Published - 9 August, 2017    By - Dr Clemens
Validation of Innovative Techniques for Monitoring Nociception during General Anesthesia: A Clinical Study Using Tetanic and Intracutaneous Electrical Stimulation

Authors: Sandra Funcke, M.D. et al Anesthesiology 8 2017, Vol.127, 272-283. Background: This study compares the analgesic indices Analgesia Nociception Index (heart rate variability), Surgical Pleth Index (photoplethysmography), and pupillary dilatation, to heart rate, mean arterial pressure, and bispectral index, with regard to diagnostic accuracy and prediction probability for nociceptive response. The primary endpoint was the correlation […]

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Uncategorized Published - 9 August, 2017    By - Dr Clemens
Association between Exposure of Young Children to Procedures Requiring General Anesthesia and Learning and Behavioral Outcomes in a Population-based Birth Cohort

Authors: Danqing Hu, M.D. et al Anesthesiology 8 2017, Vol.127, 227-240. Background: Exposure of young animals to general anesthesia causes neurodegeneration and lasting behavioral abnormalities; whether these findings translate to children remains unclear. This study used a population-based birth cohort to test the hypothesis that multiple, but not single, exposures to procedures requiring general anesthesia before age […]

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