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Uncategorized Published - 22 February, 2018    By - Dr Clemens
Monitoring for Opioid-Induced Respiratory Depression

Authors: Rajnish K. Gupta, MD, and David A. Edwards, MD, PhD. In 2006 and 2011, the Anesthesia Patient Safety Foundation (APSF) convened multidisciplinary conferences to address the serious patient safety issue of Opioid-Induced Ventilatory Impairment (OIVI).1Given the significance of the problem, and that no best monitor exists for detection of OIVI associated-adverse events, the consensus […]

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Uncategorized Published - 21 February, 2018    By - Dr Clemens
Using Activity Trackers to Quantify Postpartum Ambulation: A Prospective Observational Study of Ambulation after Regional Anesthesia and Analgesia Interventions

Authors: Julia Ma, B.Sc., M.P.H. et al Anesthesiology 3 2018, Vol.128, 598-608. Background: Early postoperative ambulation is associated with enhanced functional recovery, particularly in the postpartum population, but ambulation questionnaires are limited by recall bias. This observational study aims to objectively quantify ambulation after neuraxial anesthesia and analgesia for cesarean delivery and vaginal delivery, respectively, by using […]

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Uncategorized Published - 21 February, 2018    By - Dr Clemens
Sevoflurane Blocks the Induction of Long-term Potentiation When Present during, but Not When Present Only before, the High-frequency Stimulation

Authors: Jinyang Liu, M.S. et al Anesthesiology 3 2018, Vol.128, 555-563. Background: This study tests the hypothesis that sevoflurane blocks long-term potentiation only if it is present during the high-frequency stimulation that induces long-term potentiation. Methods: Long-term potentiation, an electrophysiologic correlate of memory, was induced by high-frequency stimulation and measured as a persistent increase in the field excitatory […]

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Uncategorized Published - 21 February, 2018    By - Dr Clemens
Physiologic Evaluation of Ventilation Perfusion Mismatch and Respiratory Mechanics at Different Positive End-expiratory Pressure in Patients Undergoing Protective One-lung Ventilation

Authors: Savino Spadaro, M.D., Ph.D. et al Anesthesiology 3 2018, Vol.128, 531-538. Background: Arterial oxygenation is often impaired during one-lung ventilation, due to both pulmonary shunt and atelectasis. The use of low tidal volume (VT) (5 ml/kg predicted body weight) in the context of a lung-protective approach exacerbates atelectasis. This study sought to determine the combined physiologic effects […]

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Uncategorized Published - 21 February, 2018    By - Dr Clemens
Four Types of Pulse Oximeters Accurately Detect Hypoxia during Low Perfusion and Motion

Authors: Aaron Louie, B.S. et al Anesthesiology 3 2018, Vol.128, 520-530. Background: Pulse oximeter performance is degraded by motion artifacts and low perfusion. Manufacturers developed algorithms to improve instrument performance during these challenges. There have been no independent comparisons of these devices. Methods: We evaluated the performance of four pulse oximeters (Masimo Radical-7, USA; Nihon Kohden OxyPal Neo, […]

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