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AUTHORS: Sherman, Jodi, D., MD et al Anesthesia & Analgesia: January 9, 2018 BACKGROUND: Traditional medical device procurement criteria include efficacy and safety, ease of use and handling, and procurement costs. However, little information is available about life cycle environmental impacts of the production, use, and disposal of medical devices, or about costs incurred after purchase. Reusable […]
Read MoreAUTHORS: Jerath, Angela, FRCPC, FANZCA, MBBS, BSc et al Anesthesia & Analgesia: January 5, 2018 BACKGROUND: Tranexamic acid (TXA) is a common antifibrinolytic agent used to minimize bleeding in cardiac surgery. Up to 50% cardiac surgical patients have chronic renal dysfunction (CRD). Optimal dosing of TXA in CRD remains poorly investigated. This is important as TXA is […]
Read MoreAUTHORS: Nakamura, Sayaka, MD et al Anesthesia & Analgesia: May 2018 – Volume 126 – Issue 5 – p 1617–1623 BACKGROUND: Inadequate or excess administration of unfractionated heparin for cardiopulmonary bypass (CPB) can cause significant harm. Age-dependent differences in the pharmacodynamics and pharmacokinetics of heparin contribute to increased variability of heparin responsiveness in children. The aims of […]
Read MoreMax Baker would have been 24 years old on his next birthday, and likely a budding medical school student with aspirations of helping young people with opioid addiction. But Max never lived to see that day. Instead, Max was the victim of a long-time opioid addiction that, while under control, proved deadly following preoperative administration […]
Read MoreIn what might be the first study of its kind, a team of French researchers has found that an individualized tight approach to blood pressure management reduces the risk for postoperative organ dysfunction compared with standard hemodynamic management. These results, they noted, have far-reaching implications given how common hemodynamic instability and arterial hypotension are during […]
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