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Intrathecal drug delivery systems may be ineffective in reducing pain and oral opioid intake in individuals with complex regional pain syndrome, according to a study recently published in Pain Medicine. This study included 1653 individuals with implanted intrathecal drug delivery systems, 62 of whom had received the device to alleviate complex regional pain syndrome-related pain(n=26 with ≥ 4 […]
Read MoreAuthors: Merrick Miles, MD and Kimberley Nichols, MD Anesthesiology News Dural puncture after labor epidural placement occurs in up to 1.5% of parturients.1 Many factors have been hypothesized that might put a patient at risk for dural puncture, such as a large needle gauge and patient position during placement. However, a history of prior epidural steroid injections has not […]
Read MoreAuthor: Thomas Rosenthal Anesthesiology News Dexmedetomidine offers several important advantages for weaning patients off mechanical ventilation in the ICU. But whether the drug is a clear-cut front-runner for these patients—particularly the 15% who prove resistant to such weaning—needs further study, Gilles L. Fraser, PharmD, MCCM, noted during the 2018 annual congress of the Society of Critical […]
Read MoreAuthors: Haidl F et al Acta Anaesthesiologica Scandinavica (Jun 2018) BACKGROUND The combination of low-dose local anesthesia and lipophilic opioids such as fentanyl is established as a standard solution for labor epidural analgesia. Fentanyl increases efficacy, but may have negative effects on the neonate in terms of reduced neonatal neurologic and adaptive capacity scores and […]
Read MoreAuthors: Hovaguimian F et al Acta Anaesthesiologica Scandinavica (Jun 2018) BACKGROUND Postoperative cognitive complications are associated with substantial morbidity and mortality. Ketamine has been suggested to have neuroprotective effects in various settings. This systematic review evaluates the effects of intraoperative ketamine administration on postoperative delirium and postoperative cognitive dysfunction (POCD). METHODS Medline, Embase and Central […]
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