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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Aquaporin 5 –1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome

Authors: Tim Rahmel, M.D. et al Anesthesiology 3 2019, Vol.130, 404-413. What We Already Know about This Topic: Acute respiratory distress syndrome is defined according to clinical criteria, but lack of precise characterization may contribute to negative trials and impede personalized care. Polymorphisms of aquaporin-5, a key mediator of inflammation, may impact outcome. What This Article […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

Authors: Fleur S. Meijer, M.D. et al Anesthesiology 5 2019, Vol.130, 745-755. What We Already Know about This Topic: The nociception level index (Medasense Biometrics Ltd., Ramat Gan, Israel), is a reliable measure of moderate to intense noxious stimulation during anesthesia and surgery What This Article Tells Us That Is New: In a randomized trial in […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
US Cancer Patients Are Undergoing CRISPR Tests For The First Time

By David Grossman Popular Mechanics The high-profile experimental technique got a bad rap in 2018. Scientists are trying for a second introduction in 2019. For the first time, doctors in the United States have used cutting-edge CRISPR technology to treat cancer patients. Two cancer patients participating in a study with the University of Pennsylvania in […]

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Uncategorized Published - 22 April, 2019    By - Dr Clemens
Driving Pressure during Thoracic Surgery: A Randomized Clinical Trial

Authors: MiHye Park, M.D. et al Anesthesiology 3 2019, Vol.130, 385-393. What We Already Know about This Topic: Driving pressure (plateau minus end-expiratory airway pressure) is a target in patients with acute respiratory distress syndrome, and is proposed as a target during general anesthesia for patients with normal lungs. It has not been reported for […]

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Uncategorized Published - 22 April, 2019    By - Dr Clemens
Narcolepsy, Anesthesia, and Sedation

AUTHORS: Hershner, Shelley, MD et al Anesthesia & Analgesia: December 2018 A Survey of the Perioperative Experience of Patients With Narcolepsy BACKGROUND: Patients with narcolepsy may be at increased perioperative risk due to the interactions among anesthesia, narcolepsy, and narcolepsy medications. This study sought to determine the perioperative experience of narcoleptic patients undergoing anesthesia or sedation, the […]

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