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AUTHORS: Lachmann, Gunnar MD et al Anesthesia & Analgesia: March 4, 2019 – BACKGROUND: Skeletal muscle failure in critical illness (intensive care unit-acquired weakness) is a well-known complication developing early during intensive care unit stay. However, muscle weakness during the perioperative setting has not yet been investigated. METHODS: We performed a subgroup investigation of a prospective observational trial […]
Read MoreAuthors: Pardo J et al Clinical Journal of Pain (Feb 2019) OBJECTIVES Fibromyalgia syndrome (FMS) is a chronically painful condition whose symptoms are widely reported to be exacerbated by stress. We hypothesized that female patients with FMS differ from healthy female controls in their sympathetic responses, a fact that may unmask important biomarkers and factors […]
Read MoreAuthors: Hernández G et al. JAMA 2019 Feb 19 Capillary refill–guided treatment compared favorably to lactate measurement. We don’t know the best markers to assess adequate resuscitation of patients with sepsis. Although the Surviving Sepsis guidelines endorse using lactate clearance as guidance, it is a weak recommendation with low-quality evidence (NEJM JW Emerg Med Jun 2018 and Intensive […]
Read MoreMIT Technology Review An unnamed man in London has become the second person worldwide to be cleared of HIV, although it is too early to say he has been “cured.” The details: The patient received a stem cell transplant from a donor with a rare genetic mutation that makes them HIV-resistant. Specifically, the donor had two copies […]
Read MoreAuthors: Nielsen AO et al. EClinicalMedicine 2019 Jan Hospitalizations for chronic obstructive pulmonary disease were less common in patients who received β-blockers. Patients with chronic obstructive pulmonary disease (COPD) often do not receive β-blockers because of concerns that they might exacerbate respiratory symptoms. Using Danish registries from 1995 to 2015, investigators studied the incidence of COPD […]
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