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Uncategorized Published - 17 April, 2020    By - Dr Clemens
FDA reports more shortages of drugs used to put COVID-19 patients on ventilators

Increasing demand for sedatives used to help put COVID-19 patients onto ventilators means the US Food and Drug Administration (FDA) added two more – this time the injectables propofol and dexmedetomidine – to its list of drug shortages. The propofol shortage was also previously listed by the American Society for Health-System Pharmacists (ASHP) earlier this month, with […]

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Uncategorized Published - 16 April, 2020    By - Dr Clemens
Estimating the Impact of Carbon Dioxide Absorbent Performance Differences on Absorbent Cost During Low-Flow Anesthesia

AUTHORS: Feldman, Jeffrey M. MD, MSE et al Anesthesia & Analgesia: February 2020 – Volume 130 – Issue 2 – p 374-381 BACKGROUND:  Reducing fresh gas flow when using a circle anesthesia circuit is the most effective strategy for reducing both inhaled anesthetic vapor cost and waste. As fresh gas flow is reduced, the amount […]

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Uncategorized Published - 16 April, 2020    By - Dr Clemens
Effect of Sugammadex on Postoperative Myasthenic Crisis in Myasthenia Gravis Patients

AUTHORS: Mouri, Hideyuki MD et al Anesthesia & Analgesia: February 2020 – Volume 130 – Issue 2 – p 367-373 BACKGROUND:  In myasthenia gravis (MG) patients, postoperative myasthenic crisis, and residual neuromuscular blocking agent (NMBA) can cause respiratory failure that requires mechanical ventilation. However, it remains unclear whether the use of sugammadex for NMBA reversal […]

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Uncategorized Published - 16 April, 2020    By - Dr Clemens
Effect of Sevoflurane Versus Isoflurane on Emergence Time and Postanesthesia Care Unit Length of Stay

AUTHORS: Maheshwari, Kamal MD, MPH et al Anesthesia & Analgesia: February 2020 – Volume 130 – Issue 2 – p 360-366 BACKGROUND:  We previously reported that the duration of hospitalization was not different between isoflurane and sevoflurane. But more plausible consequences of using soluble volatile anesthetics are delayed emergence from anesthesia and prolonged stays in […]

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Uncategorized Published - 16 April, 2020    By - Dr Clemens
Ability of an Arterial Waveform Analysis–Derived Hypotension Prediction Index to Predict Future Hypotensive Events in Surgical Patients

AUTHORS: Davies, Simon James MD et al Anesthesia & Analgesia: February 2020 – Volume 130 – Issue 2 – p 352-359 BACKGROUND:  Intraoperative hypotension is associated with worse perioperative outcomes for patients undergoing major noncardiac surgery. The Hypotension Prediction Index is a unitless number that is derived from an arterial pressure waveform trace, and as […]

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