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Anesthesiology Published - 26 December, 2025    By - Dr Clemens
A Systematic Review of Postoperative Care Transition Interventions: Examining the Implementation of Handoff Protocols and Checklists

Authors: Duffy CC et al. Anesthesia & Analgesia. 141(6):1237–1244, December 2025. SummaryThis systematic review examined perioperative postoperative care transition (handoff) interventions, focusing specifically on how handoff protocols and checklists are implemented and whether they improve clinical outcomes. The authors highlight that handoffs are a high-risk period for communication failures and loss of critical patient information, […]

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Anesthesiology Published - 26 December, 2025    By - Dr Clemens
Single-Syringe Total Intravenous Anesthesia With Propofol and Remifentanil

Authors: Bennion N et al. Anesthesia & Analgesia. 141(6):1230–1233, December 2025. SummaryThis prospective, single-center observational cohort study evaluated the effectiveness and safety of administering propofol and remifentanil as a combined single-syringe total intravenous anesthesia (TIVA) technique. While standard practice typically uses separate infusion pumps, this institution has employed a single-syringe approach for more than 25 […]

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Anesthesiology Published - 26 December, 2025    By - Dr Clemens
Modulation of pain sensitivity by the locus coeruleus–paraventricular thalamic nucleus–anterior cingulate cortex pathway in mice

Authors: Kuai S et al. Anesthesiology. December 2025. DOI: 10.1097/ALN.0000000000005897 SummaryThis preclinical study investigated how noradrenergic signaling from the locus coeruleus (LC) modulates pain sensitivity through interactions with the paraventricular thalamic nucleus (PVA) and the anterior cingulate cortex (ACC). While LC projections to both the thalamus and cortex have been implicated in pain processing, the […]

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Anesthesiology Published - 26 December, 2025    By - Dr Clemens
Respiratory and antinociceptive effects of NOP-MOP agonist cebranopadol versus full opioid receptor agonist oxycodone

Authors: Jansen S et al. Anesthesiology. December 2025. DOI: 10.1097/ALN.0000000000005894 SummaryThis randomized, double-blind, placebo-controlled study compared the respiratory and antinociceptive effects of the dual nociceptin–mu opioid receptor (NOP–MOP) agonist cebranopadol with the full mu-opioid receptor agonist oxycodone in healthy volunteers. The rationale for the study stems from preclinical and early clinical data suggesting that NOP […]

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Anesthesiology Published - 26 December, 2025    By - Dr Clemens
Challenges that will plague anesthesia into 2026

 Author: Cameron Cortigiano Becker’s ASC Review The lack of reimbursements, staffing shortages and cost challenges are some of the biggest hurdles for anesthesia providers and groups heading into next year. Two leaders recently connected with Becker’s to share what they believe will be the toughest challenges for the anesthesia space in 2026. Note: Responses were lightly edited […]

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