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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Driving Pressure–Guided Individualized Positive End-Expiratory Pressure in Abdominal Surgery:

AUTHORS: Zhang, Chengmi MD, PhD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1197-1205 BACKGROUND:  The optimal positive end-expiratory pressure (PEEP) to prevent postoperative pulmonary complications (PPCs) remains unclear. Recent evidence showed that driving pressure was closely related to PPCs. In this study, we tested the hypothesis that an […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Neurocognitive, Quality of Life, and Behavioral Outcomes for Patients With Covert Stroke After Cardiac Surgery

AUTHORS: Lewis, Choy MD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1187-1196 BACKGROUND:  Asymptomatic brain ischemic injury detected with diffusion-weighted magnetic resonance imaging (DWI) is reported in more than one-half of patients after cardiac surgery. There are conflicting findings on whether DWI-detected covert stroke is associated with neurocognitive […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Survey of Practice Pattern in Patients With Heparin-Induced Thrombocytopenia Requiring Cardiopulmonary Bypass

AUTHORS: Wanat-Hawthorne, Alycia MD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1180-1186 BACKGROUND:  Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse reaction to heparin. Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are routinely anticoagulated with heparin before the initiation of bypass. Heparin is contraindicated, however, in patients with […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Relationship Between the Loaded Pressure and Flow Rate of Packed Red Blood Cells and Various Infusion Solutions in Normal Infusion Lines and Catheters

AUTHORS: Miyoshi, Hirotsugu MD, PhD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1107-1115   BACKGROUND:  We investigated the relationship between the loaded pressure and flow rate in various catheters and the entire infusion line including the catheters, in several infusion solutions and packed red blood cells. METHODS: We […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Anesthetic Effects on the Progression of Parkinson Disease in the Rat DJ-1 Model

AUTHORS: Xu, Daniel A. BS et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1140-1151 BACKGROUND:  Parkinson disease is a chronic and progressive movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The causes of Parkinson disease are not clear but may involve […]

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