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Uncategorized Published - 12 November, 2021    By - Dr Clemens
Persistent Postoperative Opioid Prescription Fulfillment and Peripheral Nerve Blocks for Ambulatory Shoulder Surgery

Authors: Gavin M. Hamilton, M.D., M.Sc. et al  Anesthesiology November 2021, Vol. 135, 829–841. Background There is need to identify perioperative interventions that decrease chronic opioid use. The authors hypothesized that receipt of a peripheral nerve block would be associated with a lower incidence of persistent postoperative opioid prescription fulfillment. Methods This was a retrospective […]

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Uncategorized Published - 12 November, 2021    By - Dr Clemens
The Programmed Cell Death Ligand-1/Programmed Cell Death-1 Pathway Mediates Pregnancy-Induced Analgesia via Regulating Spinal Inflammatory Cytokines

AUTHORS: Tan, HuiLing MD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1321-1330 BACKGROUND:  The maternal pain threshold gradually increases during pregnancy, especially in late pregnancy. A series of mechanisms underlying pregnancy-induced analgesia have been reported. However, these mechanisms are still not completely clear, and the underlying molecular mechanisms […]

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Uncategorized Published - 12 November, 2021    By - Dr Clemens
Safety of Continuous Erector Spinae Catheters in Chest Trauma

AUTHORS: White, L. D. MBBS et al  Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1296-1302 BACKGROUND:  The erector spinae block is an efficacious analgesic option for the management of rib fracture–related pain. Despite there being minimal published data specifically addressing the safety profile of this block, many societies have made […]

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Uncategorized Published - 12 November, 2021    By - Dr Clemens
Respiratory Drive in Patients with Sepsis and Septic Shock: Modulation by High-flow Nasal Cannula

Authors:  Tommaso Mauri, M.D. et al  Anesthesiology December 2021, Vol. 135, 1066–1075. Background Experimental and pilot clinical data suggest that spontaneously breathing patients with sepsis and septic shock may present increased respiratory drive and effort, even in the absence of pulmonary infection. The study hypothesis was that respiratory drive and effort may be increased in […]

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Uncategorized Published - 12 November, 2021    By - Dr Clemens
A Case Report from the Anesthesia Incident Reporting System: Operating in a digital vacuum

ASA Monitor October 2020, Vol. 84, 13–14. An active 4-year-old girl underwent anesthesia for routine MRI evaluation of medulloblastoma at a freestanding health care facility. Multiple previous anesthetics for the same investigation were noted to be uneventful. The parental MRI screening questionnaire noted a potential past reaction to contrast in another medical facility, which the […]

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