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Uncategorized Published - 14 December, 2021    By - Dr Clemens
Comparison of a Nasal Mask and Traditional Nasal Cannula During Intravenous Anesthesia for Gastroscopy Procedures

AUTHORS: Chen, Dong Xu MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Hypoxemia can occur during gastroscopy under intravenous anesthesia. The aim of this randomized controlled trial was to evaluate whether oxygenation using a nasal mask can reduce the incidence of hypoxemia during gastroscopy under intravenous anesthesia compared with a traditional nasal cannula. METHODS: A […]

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Uncategorized Published - 14 December, 2021    By - Dr Clemens
Chronic Pain Following Fracture-Related Surgery

AUTHORS: Aulenkamp, Jana L. MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Chronic posttraumatic/postsurgical pain (CPSP) is common after traumatic or surgical damage. Exposure to both trauma and surgery, with the potential for repeated bone and nerve damage, may increase the risk of CPSP after fracture-related surgery. But the (long-term) incidences of CPSP and neuropathic […]

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Uncategorized Published - 13 December, 2021    By - Dr Clemens
Polymorphic Variants in the GRK5 Gene Promoter Are Associated With Diastolic Dysfunction in Coronary Artery Bypass Graft Surgery Patients

AUTHORS: Fassbender, Philipp MD et al Anesthesia & Analgesia: December 2021 – Volume BACKGROUND: The G-protein–coupled receptor kinase 5 (GRK5) is a mediator of cardiovascular homeostasis and participates in inflammation and cardiac fibrosis, both being involved in the development of diastolic dysfunction (DD). While mechanisms of transcriptional regulation of the GRK5 promoter are unclear, we tested […]

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Uncategorized Published - 13 December, 2021    By - Dr Clemens
The Relation Between Mean Arterial Pressure and Cardiac Index in Major Abdominal Surgery Patients

AUTHORS: Kouz, Karim MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Cardiac output is an important hemodynamic variable and determines oxygen delivery. In contrast to blood pressure, cardiac output is rarely measured even in high-risk surgical patients, suggesting that clinicians consider blood pressure to be a reasonable indicator of systemic blood flow. However, the relationship […]

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Uncategorized Published - 13 December, 2021    By - Dr Clemens
Hydroxyethyl Starch for Fluid Management in Patients Undergoing Major Abdominal Surgery

AUTHORS: Pensier, Joris MD et al Anesthesia & Analgesia: November 2021 BACKGROUND: In critically ill patients, warnings about a risk of death and acute kidney injury (AKI) with hydroxyethyl starch (HES) solutions have been raised. However, HES solutions may yet have a role to play in major abdominal surgery. This meta-analysis and trial sequential analysis (TSA) […]

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