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Uncategorized Published - 4 January, 2022    By - Dr Clemens
Age-Specific Clinical Features of Pediatric Malignant Hyperthermia

AUTHORS: Otsuki, Sachiko MD, PhD et al Anesthesia & Analgesia: December 28, 2021 BACKGROUND: Malignant hyperthermia (MH) is an inherited muscle disorder induced by volatile anesthetics and depolarizing muscle relaxants. While the incidence of MH is high in young, there are few reports on the clinical features of pediatric MH. In this study, we selected pediatric […]

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Uncategorized Published - 4 January, 2022    By - Dr Clemens
Challenges of Pediatric Anesthesia Services and Training Infrastructure in Tertiary Care Teaching Institutions in Pakistan

AUTHORS: Khan, Fauzia A. MBBS, FRCA et al Anesthesia & Analgesia: December 28, 2021 BACKGROUND: Pakistan is a lower middle–income country located in South Asia with a population of nearly 208 million. Sindh is its second largest province. The aim of this survey was to identify the current setup of pediatric services, staffing, equipment, and training […]

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Uncategorized Published - 3 January, 2022    By - Dr Clemens
Inflammatory Biomarker Levels After Propofol or Sevoflurane Anesthesia

AUTHORS:  O’Bryan, Liam J. MD et al Anesthesia & Analgesia: January 2022 – Volume 134 – Issue 1 – p 69-81 BACKGROUND:  The perioperative inflammatory response may be implicated in adverse outcomes including neurocognitive dysfunction and cancer recurrence after oncological surgery. The immunomodulatory role of anesthetic agents has been demonstrated in vitro; however, its clinical relevance […]

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Uncategorized Published - 3 January, 2022    By - Dr Clemens
The Relation Between Mean Arterial Pressure and Cardiac Index in Major Abdominal Surgery Patients

AUTHORS: Kouz, Karim MD et al  Anesthesia & Analgesia: December 10, 2021 BACKGROUND: Cardiac output is an important hemodynamic variable and determines oxygen delivery. In contrast to blood pressure, cardiac output is rarely measured even in high-risk surgical patients, suggesting that clinicians consider blood pressure to be a reasonable indicator of systemic blood flow. However, the […]

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Uncategorized Published - 3 January, 2022    By - Dr Clemens
Hydroxyethyl Starch for Fluid Management in Patients Undergoing Major Abdominal Surgery

AUTHORS: Pensier, Joris MD et al  Anesthesia & Analgesia: November 22, 2021 Abstract BACKGROUND: In critically ill patients, warnings about a risk of death and acute kidney injury (AKI) with hydroxyethyl starch (HES) solutions have been raised. However, HES solutions may yet have a role to play in major abdominal surgery. This meta-analysis and trial sequential […]

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