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AUTHORS: Duprey, Matthew S. PharmD, PhD et al Anesthesia & Analgesia: February 2022 BACKGROUND: Postoperative delirium is frequent in older adults and is associated with postoperative neurocognitive disorder (PND). Studies evaluating perioperative medication use and delirium have generally evaluated medications in aggregate and been poorly controlled; the association between perioperative medication use and PND remains unclear. […]
Read MoreDG Journal Club AUTHORS: Yu-Chen Cheng et al J Headache Pain. 2022 Feb 20; 23(1): 28 BACKGROUND Current pharmacologic prophylactic strategies for migraine have exhibited limited efficacy, with response rates as low as 40%-50%. In addition to the limited efficacy, the acceptability of those pharmacologic prophylactic strategies were unacceptable. Although noninvasive brain/nerve stimulation strategies may […]
Read MoreAUTHORS: Jokinen, Johan D. V. MD et al Anesthesia & Analgesia: February 2022 BACKGROUND: New-onset postoperative atrial fibrillation (POAF) is associated with several cardiovascular complications and higher mortality. Several pathophysiological processes such as hypoxia can trigger POAF, but these are sparsely elucidated, and POAF is often asymptomatic. In patients undergoing major gastrointestinal cancer surgery, we aimed […]
Read MoreAUTHORS: Truong, Tien M. PharmD, PhD et al Anesthesia & Analgesia: February 2022 BACKGROUND: Pharmacogenomics, which offers a potential means by which to inform prescribing and avoid adverse drug reactions, has gained increasing consideration in other medical settings but has not been broadly evaluated during perioperative care. METHODS: The Implementation of Pharmacogenomic Decision Support in Surgery […]
Read MoreAuthor: Valencin Higuera MedicalNewsToday Alcoholic hepatitis is an inflammatory liver condition. The main cause is frequent, heavy alcohol use. Processing excessive amounts of alcohol can result in injury to the liver cells, which can lead to swelling and scarring of the liver. The condition can be mild or severe. In severe cases, a person may […]
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