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Authors: Bi L. Li, M.D. et al Anesthesiology June 2022. Background Intranasal dexmedetomidine provides noninvasive, effective procedural sedation for pediatric patients, and has been widely used in clinical practice. However, the dosage applied has varied fourfold in pediatric clinical studies. To validate an appropriate dosing regimen, this study investigated the pharmacokinetics of intranasal dexmedetomidine in Chinese […]
Read MoreAuthors: Naveen Vanga, M.D. et al Anesthesiology July 2022, Vol. 137, 114–116. The supraglottic airway has proven its versatility in the operating room emergency room, and field resuscitation. However, the risk of pulmonary aspiration associated with supraglottic airways still exists. The fundamental design of the supraglottic airway has not been significantly changed since its inauguration in the 1980s. Second-generation supraglottic […]
Read MoreAuthors: Ian Yuan, M.D. et al Anesthesiology June 2022. Background Intraoperative isoelectric electroencephalography (EEG) has been associated with hypotension and postoperative delirium in adults. This international prospective observational study sought to determine the prevalence of isoelectric EEG in young children during anesthesia. The authors hypothesized that the prevalence of isoelectric events would be common worldwide […]
Read MoreAuthors: Romein W. G. Dujardin, M.D. et al Anesthesiology June 2022. Background Viscoelastic hemostatic assays such as rotational thromboelastometry (ROTEM) are used to guide treatment of trauma induced coagulopathy. The authors hypothesized that ROTEM derangements reflect specific coagulation factor deficiencies after trauma. Methods This was a secondary analysis of a prospective cohort study in six […]
Read MoreAuthors: Sergey Karamnov, M.D.; Jochen D. Muehlschlegel, M.D., M.M.Sc., M.B.A. Anesthesiology June 2022, Vol. 136, 877–879. “…postoperative atrial fibrillation is not a transient benign phenomenon but rather an ominous postoperative complication associated with increased risk of thromboembolism, stroke, and mortality.” Postoperative atrial fibrillation is one of the most common complications after thoracic noncardiac surgery. Despite contemporary prevention […]
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