NEJM Journal Watch Bruce Soloway, MD, reviewing Katsoularis I et al. BMJ 2022 Apr 6 But risks are less elevated for those who do not require hospitalization. People with severe COVID-19 are at excess risk for venous thromboembolism (VTE), but whether risk also rises among patients with mild disease is unclear. Using Swedish national health databases, researchers identified […]
Read MoreAUTHORS: Abe, Hiroaki MD, PhD et al Anesthesia & Analgesia: May 16, 2022 BACKGROUND: It is unclear whether gabapentinoids affect the development of delirium. We aimed to determine the association between gabapentinoid use and hyperactive delirium in older cancer patients undergoing chemotherapy. METHODS: We conducted propensity score-matched analyses using data from a nationwide inpatient database in […]
Read MoreAUTHORS: Vikki Wylde et al Arthritis Care Res (Hoboken). 2022 May; 74(5): 790-798 OBJECTIVE To describe the screening and recruitment process of a randomized trial and evaluate associations with knee pain and function 3 months after total knee replacement (TKR). METHODS In order to screen for a multicenter trial, a total of 5,036 patients were […]
Read MoreAUTHORS: Kim, Soo Yeon MD, PhD et al Anesthesia & Analgesia: May 13, 2022 BACKGROUND: The pupillary dilation reflex (PDR), the change in pupil size after a nociceptive stimulus, has been used to assess antinociception during anesthesia. The aim of this study was to compare the antinociceptive properties of sevoflurane and desflurane by measuring the PDR […]
Read MoreAUTHORS: Togioka, Brandon M. MD et al Anesthesia & Analgesia: May 12, 2022 BACKGROUND: Intraperitoneal chloroprocaine has been used during cesarean delivery to supplement suboptimal neuraxial anesthesia for decades. The short in vitro half-life of chloroprocaine (11–21 seconds) has been cited to support the safety of this approach. However, there are no data regarding the rate […]
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