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Uncategorized Published - 15 July, 2022    By - Dr Clemens
Desflurane and remifentanil anesthesia in a child with citrin deficiency

A case report Authors: Kim, Kanghui MD; Jung, Sung Mee MD, PhD∗ Editor(s): Saranathan., Maya Medicine: March 04, 2022 – Volume 101 – Issue 9 – p e28954 Rationale: Hyperammonemia, metabolic derangement, and/or the prolonged effects of anesthetics may lead to delayed emergence from general anesthesia as well as the onset of type 2 citrullinemia, even […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Perioperative Considerations of Cannabis Use on Anesthesia Administration

Authors: Dylan Irvine, BScH; Tricia Meyer, PharmD, MS; John Williams, MD; Jeffrey Huang, MD Anesthesia Pateitn Safety Foundation Volume 37, No. 2 June 2022  Introduction As of 2018, an estimated 9.5% of the United States adult population were cannabis users.1 This percentage has likely continued to increase with the use of both recreational and medicinal cannabis […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Estimates of Probabilities of Successful Development of Pain Medications

AUTHORS: Dermot P. Maher, M.D., M.S., M.H.S. et al  Anesthesiology June 2022. Background The authors estimate the probability of successful development and duration of clinical trials for medications to treat neuropathic and nociceptive pain. The authors also consider the effect of the perceived abuse potential of the medication on these variables. Methods This study uses […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Extracorporeal membrane oxygenation in coronavirus disease 2019

AUTHORS: Friedrichson, Benjamin et al  European Journal of Anaesthesiology: May 2022 – Volume 39 – Issue 5 – p 445-451 BACKGROUND In the context of the coronavirus disease 2019 (COVID-19) pandemic, many retrospective single-centre or specialised centre reports have shown promising mortality rates with the use of extracorporeal membrane oxygenation (ECMO) therapy. However, the mortality rate […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
The Effect of Duloxetine on Mechanistic Pain Profiles, Cognitive Factors, and Clinical Pain in Patients with Painful Knee Osteoarthritis

AUTHORS: Kristian Kjaer-Staal Petersen et al Eur J Pain. 2022 May 31 BACKGROUND Duloxetine is indicated in the management of pain in osteoarthritis. Evidence suggests that duloxetine modulate central pain mechanisms and cognitive factors, and these factors are assumed contributing to the analgesic effect. This proof-of-mechanism, randomized, placebo-controlled, crossover, double-blinded trial evaluated the effect of […]

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