Author: Ono S et al.
Anesthesiology. doi:10.1097/ALN.0000000000005689
This multicenter retrospective study in Japan analyzed data from 8,794 patients with Rapid Response System (RRS) activations across 35 hospitals (2018–2022) to evaluate the relationship between institutional ICU admission practices and patient outcomes. For each hospital, investigators calculated the ICU admission rate and the Standardized ICU Admission Ratio (SIAR), defined as the ratio of actual to predicted ICU admissions.
Median ICU admission rate was 0.33, and median SIAR was 0.98. Higher SIAR values correlated with improved outcomes, showing a significant association with lower rates of “Cerebral Performance Category ≥ 3 or death within 30 days” (multivariable OR per 0.1 increase in SIAR = 0.94; 95% CI, 0.92–0.96; P < 0.001). The association with “death within 30 days” alone was not statistically significant.
The authors conclude that greater ICU utilization after RRS activation may reduce poor neurologic outcomes or death within 30 days, although further research is needed to determine causal mechanisms.
References
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Ono S, Uchino S, Tokito M, et al. Anesthesiology. 2025. doi:10.1097/ALN.0000000000005689.
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