When the Drip Stops: The Intravenous Fluid Shortage

Authors: Song, Soobin MS, BS; Hoggard, MaKayla BS; Ortega, Rafael MD

Anesthesia & Analgesia ():10.1213/ANE.0000000000007372, January 27, 2025. 

To the Editor

The recent intravenous (IV) fluid shortage in the United States is a stark reminder of the fragility of resource availability, sending ripples of concern throughout the medical community. Triggered by Hurricane Helene’s damage to a major production plant in North Carolina, the scarcity has forced hospitals, long accustomed to abundant supply, to suddenly ration a critical therapeutic tool. From operating rooms to emergency departments, clinicians are compelled to prioritize oral hydration and utilize smaller fluid bags. While disruptive, this crisis offers a valuable opportunity to reassess and research the impact of judicious fluid use on patient outcomes. Are we, in fact, hydrating our patients when not indicated? Can we achieve similar clinical results with less aggressive fluid administration? These are questions that deserve further investigation.

The shortage underscores a critical vulnerability: the overreliance on single points of failure in the medical supply chain. Just as the coronavirus disease-2019 (COVID-19) pandemic exposed our dependence on foreign manufacturers for personal protective equipment, the IV fluid crisis highlights the danger of consolidated production. While consolidation offers economic benefits through economies of scale, it leaves the system susceptible to disruption from natural disasters, such as Hurricane Helene in North Carolina, industrial accidents, or even geopolitical events.

The U.S. Food and Drug Administration (FDA) maintains a drug shortage list that frequently includes essential medications. As of November 4, 2024, the database lists sodium chloride at 0.9%, dextrose at 5%, and other basic solutions as “Currently in Shortage.” These IV fluids are vital for a wide range of medical treatments, including hydration, delivering medications, and supporting patients during surgery. Alarmingly, the World Health Organization (WHO) includes these very solutions in its list of essential medicines, underscoring their critical importance for basic health care.

The United States, a nation with vast resources, must prioritize redundancy in critical medical supplies not only including IV fluids, but also essential medications and equipment. Diversifying production sources, maintaining strategic reserves, and fostering domestic manufacturing capacity are crucial steps toward building a more resilient health care system.

Furthermore, this crisis compels us to reexamine our consumption patterns. The overuse of IV fluids in hospitals, perhaps driven by a perception of abundance and low cost, seems wasteful. The forced frugality imposed by the shortage may, in fact, lead to beneficial long-term changes. By optimizing fluid management protocols and embracing a more conservative approach, we can reduce costs, minimize environmental impact, and potentially improve patient outcomes.

The IV fluid shortage is a wake-up call and reminder of the interconnectedness of global resource availability and the vulnerability of centralized production models. It is also an opportunity to reevaluate our consumption habits and prioritize sustainable practices. By learning from this experience, we can build a more resilient and responsible health care system, prepared to face the challenges of a water-stressed future.

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