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AUTHORS: Zhang, Haopeng PhD, MD et al Anesthesia & Analgesia ():10.1213/ANE.0000000000007514, April 17, 2025. BACKGROUND: Minimum alveolar concentration (MAC) is used as the standard measure of potency for volatile anesthetic agents. However, there is a lack of effective and quantitative indicator of the combined potency of multiple coadministered inhalation and intravenous anesthetics. We hypothesized that an […]
Read MoreAUTHORS: Yu, Yao MD et al Anesthesia & Analgesia ():10.1213/ANE.0000000000007584, May 23, 2025. BACKGROUND: Malignant hyperthermia (MH) is a life-threatening pharmacogenetic disorder triggered by certain anesthetics, characterized by muscle rigidity, elevated body temperature, and hypermetabolic crisis. This condition is primarily associated with genetic mutations in ryanodine receptor 1 (RYR1), which encodes the pivotal calcium release channel […]
Read MoreAuthor: Patsy Newitt Becker’s ASC Review Amid a growing anesthesia workforce shortage, stakeholders across the industry are pondering how to build a more sustainable and effective pipeline of providers. Seven anesthesia leaders connected with Becker’s to discuss their most urgent priorities for combating the shortage, from workforce collaboration to expansion of training programs. Question: What are the […]
Read MoreAuthor: Alicia Ault Medscape Anesthesiology The US Food and Drug Administration (FDA) is urging manufacturers to revise labeling of transmucosal buprenorphine products to ease access to higher doses needed due to the rise of high-potency opioids like fentanyl. The agency published its proposal in the Federal Register in late December. The move comes on the heels of […]
Read MoreIf you’re an anesthesiologist searching for a balanced lifestyle and rewarding work, you’ll want to check out this opportunity. Our all-anesthesiologist group is seeking a dedicated team member to join our collaborative practice. Position Highlights: Zero Call for 3 Weeks: Enjoy three weeks of no call duty, followed by one week of call. Even during […]
Read MoreAuthor: Jesse A. Berg Lathrop GPM On May 22, 2025, the U.S. Department of Health and Human Services, Department of Treasury and Department of Labor (the “Agencies”) announced new steps intended to “strengthen healthcare price transparency.” This guidance follows an Executive Order on price transparency issued in late February. This cross-agency effort focuses on hospitals and […]
Read MoreWe’re excited to announce the formation of a new anesthesia group in Riverdale, GA, located just 10 minutes from the Atlanta Airport. We’re seeking dedicated CRNAs to join our collaborative care team, which will include 4 full-time CRNAs and 2 anesthesiologists managing 4 operating rooms. This is a 25% independent practice and doing own blocks! […]
Read MoreAUTHORS: Goeddel, Lee A. MD, MPH et al Anesthesia & Analgesia 140(6):p 1439-1449, June 2025. BACKGROUND: Prior studies identified thresholds for mean arterial pressure (MAP <65 mm Hg) and central venous pressure (CVP >12 mm Hg) beyond which risk for cardiac surgery-associated acute kidney injury (AKI) increases. Optimal hemodynamic targets—that is, where active protection from AKI […]
Read MoreAUTHORS: Ahrens, Elena cand. med. et al Anesthesia & Analgesia ():10.1213/ANE.0000000000007489, April 18, 2025. BACKGROUND: Nondepolarizing neuromuscular blocking agents (ND-NMBAs) are dose-dependently associated with residual paralysis, delayed recovery, and prolonged hospitalization, factors that can predispose patients to postoperative delirium. We hypothesized that neuromuscular blockade is associated with a higher risk of delirium after surgery, and that […]
Read MoreAUTHORS: Soejima, Takashi MD et al Anesthesia & Analgesia ():10.1213/ANE.0000000000007572, May 23, 2025. BACKGROUND: Sepsis-associated encephalopathy causes irreversible cognitive dysfunction, yet no effective pharmacological treatments are available. The hippocampus is particularly vulnerable to sepsis-induced damage, and impairments in hippocampal synaptic plasticity, particularly late-phase long-term potentiation (L-LTP), are implicated in cognitive dysfunction. Brain-derived neurotrophic factor (BDNF) and […]
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