Month: June 2024

Uncategorized Published - 18 June, 2024    By - Dr Clemens
Unraveling a Recurrent Wrong Drug-Wrong Route Error—Tranexamic Acid in Place of Bupivacaine

Authors: Paul A. Lefebvre, JD et al  Anesthesia Safety Patient Foundation June 2024 Volume 39, No. 2  INTRODUCTION . Notwithstanding technological advances and the ongoing efforts of patient safety advocates, medication administration errors routinely occur in health care facilities across the country.1-2 Each day, anesthesia professionals overcome challenges that commonly contribute to medication errors, such as […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Opioid-Induced Respiratory Depression—Pediatric Considerations

Authors: Tricia Vecchione, MD, MPH; Constance L. Monitto, MD Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2  SUMMARY:Opioid-induced respiratory depression can be a life-threatening, albeit preventable, complication in children. It is imperative to identify those at risk for opioid-induced respiratory depression and formulate safer practices, including the use of opioid-sparing adjuncts, frequent sedation […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Association of Neighborhood Opportunity, Race and Ethnicity with Pediatric Day-of-Surgery Cancellations

Authors: Brittany L. Willer, MD et al  Anesthesiology May 2024. Background Day-of-surgery cancellations impede healthcare access and contribute to inequities in pediatric healthcare. Socially disadvantaged families have many risk factors for surgical cancellation, including low health literacy, transportation barriers, and childcare constraints. These social determinants of health are captured by the Childhood Opportunity Index (COI) […]

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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Effects of hemorrhagic shock and rhabdomyolysis on renal microcirculation, oxygenation and function in a female swine model

Authors: Benjamin Bergis, MD, Msc et al  Anesthesiology May 2024. Background Hemorrhagic shock (HS) and rhabdomyolysis (RM) are two important risk factors of acute kidney injury (AKI) after severe trauma, however the effects of the combination of RM and HS on kidney function are unknown. The purpose of this study was to determine the impact […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Combined Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Surgery of the Foot or Ankle

Authors: Mathias Maagaard, M.D. et al  Anesthesiology June 2024, Vol. 140, 1165–1175. Background Both dexamethasone and dexmedetomidine increase the duration of analgesia of peripheral nerve blocks. The authors hypothesized that combined intravenous dexamethasone and intravenous dexmedetomidine would result in a greater duration of analgesia when compared with intravenous dexamethasone alone and placebo. Methods The authors randomly […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Long-term Survival after Volatile or Propofol General Anesthesia for Bladder Cancer Surgery

Authors: Mats Enlund, M.D., Ph.D. et al  Anesthesiology June 2024, Vol. 140, 1126–1133. Background Prospective interventional trials and retrospective observational analyses provide conflicting evidence regarding the relationship between propofol versus inhaled volatile general anesthesia and long-term survival after cancer surgery. Specifically, bladder cancer surgery lacks prospective clinical trial evidence. Methods Data on bladder cancer surgery performed under general […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Intraoperative Methadone and Postoperative Anesthesia Care Unit Outcomes

Author: Evan D. Kharasch, M.D., Ph.D. Anesthesiology May 2024. To the Editor: Methadone has been used in perioperative anesthesia practice for at least four decades, and there is increasing interest in perioperative methadone use and even more so recently in both inpatients and outpatients.  Intraoperative methadone, compared with short-duration opioids, results in less postoperative opioid […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
PROBAST Assessment of Machine Learning: Comment

Authors: Elena Bignami, M.D. et al  Anesthesiology May 2024. To the Editor: We read with interest the article by Arina et al.To our knowledge, it is the most comprehensive and complete review on this topic. As underlined by the authors, the subject is very heterogeneous. For this reason and because data processing is not yet standardized, […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
PROBAST Assessment of Machine Learning: Reply

Authors: Pietro Arina, M.D. et al  Anesthesiology May 2024. In Reply: We thank Bignami et al.  for their insightful letter and their kind remarks regarding our recent publication. We fully concur that the challenge of refining search terms to enhance the specificity and breadth of literature searches is a genuine concern. This is fundamental in ensuring […]

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Uncategorized Published - 15 June, 2024    By - Dr Clemens
Paravertebral Block for Multiple Rib Fractures in an Anticoagulated Trauma Patient

 Authors: Lee M, Ayad M, Diz Ferre J L, et al. Cureus  June 06, 202416(6): e61834. Abstract This case report presents the complex analgesia management of a 52-year-old male with a significant medical history including atrial fibrillation treated with apixaban, essential trigeminal neuralgia, non-ischemic cardiomyopathy, and chronic systolic heart failure. The patient experienced a loss […]

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