Month: May 2024

Uncategorized Published - 27 May, 2024    By - Dr Clemens
Happy Memorial Day

Honoring the Heroes: A Reflection on Memorial Day I want to thank our readers and wish them a fun and safe Memorial Day. Please remember that today is a day of reflection, remembrance, and gratitude for those who laid down their lives in service to the nation. Memorial Day serves as a powerful reminder of […]

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Uncategorized Published - 24 May, 2024    By - Dr Clemens
Long-term Survival after Volatile or Propofol General Anesthesia for Bladder Cancer Surgery

Authors: Mats Enlund, M.D., Ph.D. et al  Anesthesiology June 2024, Vol. 140, 1126–1133. Background Prospective interventional trials and retrospective observational analyses provide conflicting evidence regarding the relationship between propofol versus inhaled volatile general anesthesia and long-term survival after cancer surgery. Specifically, bladder cancer surgery lacks prospective clinical trial evidence. Methods Data on bladder cancer surgery performed under general […]

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Uncategorized Published - 24 May, 2024    By - Dr Clemens
Candidate Kidney Protective Strategies for Patients Undergoing Major Abdominal Surgery

Authors: David R. McIlroy, M.D. et al  Anesthesiology June 2024, Vol. 140, 1111–1125. Background Acute kidney injury (AKI) is common after major abdominal surgery. Selection of candidate kidney protective strategies for testing in large trials should be based on robust preliminary evidence. Methods A secondary analysis of the Restrictive versus Liberal Fluid Therapy in Major Abdominal […]

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Uncategorized Published - 24 May, 2024    By - Dr Clemens
Variation in Hospital Neuraxial Labor Analgesia Rates in California

Authors: Pooja Parameshwar, M.D. et al  Anesthesiology June 2024, Vol. 140, 1098–1110. Background Neuraxial analgesia provides effective pain relief during labor. However, it is unclear whether neuraxial analgesia prevalence differs across U.S. hospitals. The aim of this study was to assess hospital variation in neuraxial analgesia prevalence in California. Methods A retrospective cross-sectional study analyzed birthing […]

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Uncategorized Published - 24 May, 2024    By - Dr Clemens
Reversal of Propofol-induced Depression of the Hypoxic Ventilatory Response by BK-channel Blocker ENA-001

Authors: Simone C. Jansen, M.D. et al  Anesthesiology June 2024, Vol. 140, 1076–1087. Background The use of anesthetics may result in depression of the hypoxic ventilatory response. Since there are no receptor-specific antagonists for most anesthetics, there is the need for agnostic respiratory stimulants that increase respiratory drive irrespective of its cause. The authors tested whether […]

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Uncategorized Published - 24 May, 2024    By - Dr Clemens
Progressing What’s Possible in Regional Anesthesia and Pain Medicine

Author: David A. Provenzano, MD ASA Monitor January 2024, Vol. 88, e4–e5. With a mission to advance the science and practice of regional anesthesia and pain medicine to improve patient outcomes, the American Society of Regional Anesthesia and Pain Medicine (ASRA Pain Medicine) is always looking at innovative, new ways to progress what’s possible. From new […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Does Propofol Improve Polyp Detection during Colonoscopy?

Authors: Douglas A. Colquhoun, M.B.Ch.B., M.Sc., M.P.H. et al  Anesthesiology June 2024, Vol. 140, 1062–1064. “Despite these limitations, this study still calls attention to the importance of preserving access to routine propofol use in patients undergoing screening and surveillance colonoscopy.” In this month’s issue of Anesthesiology, Quaye et al. report findings of their investigation into differences […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Antithrombin Deficiency during Venoarterial Extracorporeal Membrane Oxygenation: Extremely Common, but Does It Matter?

Authors: Michael Mazzeffi, M.D., M.P.H., F.A.H.A. et al  Anesthesiology June 2024, Vol. 140, 1065–1067. “Management strategies for anticoagulating adult ECMO patients and optimal management continue to be a work in progress.” In this issue of Anesthesiology, Mansour et al. explore the significance of antithrombin deficiency, defined by a time-weighted average antithrombin activity less than 70%, in adults […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Reversal for Respiratory Depression: Let’s Take a Breath!

Author: Thomas K. Henthorn, M.D. Anesthesiology June 2024, Vol. 140, 1059–1061. “Jansen et al. provide evidence that a new BK-channel blocker (i.e., ENA-001) […] may reverse the respiratory depressant effects of propofol, which may add to the utility of arousal-promoting agents and promises its own additional utility of ameliorating propofol’s respiratory depressant effects while permitting sedation.” Respiratory depression […]

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Uncategorized Published - 23 May, 2024    By - Dr Clemens
Addressing Postdural Puncture Headache: Guiding Clinicians Through Diagnosis and Management

Authors: Dibash Kumar Das, PhD; Pamela Flood, MD, MA ASA Monitor March 2024, Vol. 88, 1–4. Postdural puncture headache (PDPH) is a well-recognized complication resulting from a dural puncture during epidural analgesia, spinal anesthesia, or other neuraxial interventions. The incidence of unintended dural puncture during placement of an epidural catheter ranges widely, from less than 1% […]

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