Month: May 2024

Uncategorized Published - 3 May, 2024    By - Dr Clemens
Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery

Authors: Michael R. Mathis, M.D. et al  Anesthesiology August 2023, Vol. 139, 122–141. Background Conflicting evidence exists regarding the risks and benefits of inotropic therapies during cardiac surgery, and the extent of variation in clinical practice remains understudied. Therefore, the authors sought to quantify patient-, anesthesiologist-, and hospital-related contributions to variation in inotrope use. Methods In […]

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Uncategorized Published - 3 May, 2024    By - Dr Clemens
Sex-Specific Associations Between Preoperative Hemoglobin and Outcomes After Major Noncardiac Surgery

AUTHORS: Zhao, Bing-Cheng MD et al  Anesthesia & Analgesia 137(5):p 1019-1028, November 2023. BACKGROUND: Preoperative anemia is an established risk factor for morbidity and mortality after surgery. Men and women have different hemoglobin concentrations and are at different risks of postoperative complications. However, sex-stratified analysis on the association between preoperative hemoglobin and outcomes after noncardiac surgery […]

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Uncategorized Published - 3 May, 2024    By - Dr Clemens
Inflammatory pain affects alcohol intake in a dose-dependent manner in male rats in the intermittent access model

Authors: Campos-Jurado et al PAIN Reports 8(4):p e1082, July/August 2023. Introduction: Epidemiological studies have shown that there is a relation between pain and alcohol use disorder (AUD). Persistent pain is directly correlated with an increment in alcohol consumption and an increased risk of developing an AUD. Greater levels of pain intensity and unpleasantness are associated with […]

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Uncategorized Published - 3 May, 2024    By - Dr Clemens
Hyperoxia Increases Kidney Injury During Renal Ischemia and Reperfusion in Mice

AUTHORS: Kimlinger, Melissa J. BS et al  Anesthesia & Analgesia 137(5):p 996-1006, November 2023. BACKGROUND: Renal ischemia and reperfusion (IR) contribute to perioperative acute kidney injury, and oxygen is a key regulator of this process. We hypothesized that oxygen administration during surgery and renal IR would impact postoperative kidney function and injury in mice. METHODS: Mice […]

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Uncategorized Published - 3 May, 2024    By - Dr Clemens
Does Anesthesia Quality Improvement Participation Lead to Incremental Savings in a Surgical Quality Collaborative Population?

AUTHORS: Janda, Allison M. MD et al  Anesthesia & Analgesia 137(5):p 1093-1103, November 2023. BACKGROUND: The Anesthesiology Performance Improvement and Reporting Exchange (ASPIRE) Collaborative Quality Initiative (CQI) was launched as a partnership among hospitals to measure quality, review evidence-based practices, and improve anesthesia-related outcomes. Cost savings and improved patient outcomes have been associated with surgical CQI […]

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Uncategorized Published - 2 May, 2024    By - Dr Clemens
Anesthesia for pediatric magnetic resonance imaging

Authors: Guimarães Ferreira et al  Current Opinion in Anaesthesiology 36(4):p 428-434, August 2023. Purpose of review Magnetic resonance imaging (MRI) is an ever-expanding investigation modality in children. This review aims to present current strategies to perform MRI in pediatrics efficiently and safely. The latest evidence on approaches, safety and costs of MRI with no sedation or […]

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Uncategorized Published - 2 May, 2024    By - Dr Clemens
Proactive Patient Safety: Focusing on What Goes Right in the Perioperative Environment

Authors: Duffy, Caoimhe MD, MSc, FCAI et al     Journal of Patient Safety 19(4):p 281-286, June 2023. Objective Adverse events in the perioperative environment, a potential risk to patients, may be mitigated by nurturing staff adaptability and resiliency. An activity called “One Safe Act” (OSA) was developed to capture and highlight proactive safety behaviors that staff […]

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Uncategorized Published - 2 May, 2024    By - Dr Clemens
Low-dose naltrexone for treatment of pain in patients with fibromyalgia

Authors: Bested, Kirsten et al  PAIN Reports 8(4):p e1080, July/August 2023. Introduction: Fibromyalgia (FM) is a chronic fluctuating, nociplastic pain condition. Naltrexone is a µ-opioid-receptor antagonist; preliminary studies have indicated a pain-relieving effect of low-dose naltrexone (LDN) in patients with FM. The impetus for studying LDN is the assumption of analgesic efficacy and thus reduction of […]

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Uncategorized Published - 2 May, 2024    By - Dr Clemens
Understanding migraine symptoms in children

Author: Christopher Medrano , MD KevinMD.com If you’ve experienced a migraine headache before, the sensation is often very distinct: throbbing pain, sensitivity to light and loud noise, and sometimes nausea and vomiting. Migraine symptoms can be uncomfortable and distressing. Equally concerning is when a migraine sufferer recognizes these symptoms in their child. Migraines typically emerge […]

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Uncategorized Published - 2 May, 2024    By - Dr Clemens
Mechanism-Based Modeling of Perioperative Variations in Hemoglobin Concentration in Patients Undergoing Laparoscopic Surgery

AUTHORS: Jaramillo, Sebastian MD et al  Anesthesia & Analgesia 138(1):p 141-151, January 2024. BACKGROUND: Hemoglobin concentration ([Hb]) in the perioperative setting should be interpreted in the context of the variables and processes that may affect it to differentiate the dilution effects caused by changes in intravascular volume. However, it is unclear what variables and processes affect […]

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