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Authors: Markus Zadrazil et al Anesthesiology April 2024. d Background Little is known about the pharmacodynamic characteristics of liposomal bupivacaine. Hypothesizing that we would not identify pharmacodynamic differences from plain bupivacaine during the initial period after administration, but would find better long-term pharmacodynamic characteristics, we designed a randomized, controlled, triple-blinded, single-center study in volunteers. Methods […]
Read MoreAuthors: Jeremy P. Walco, M.D. et al Anesthesiology April 2024. Background The relationship between postoperative adverse events and blood pressures in the preoperative period remains poorly understood. This study tested the hypothesis that day-of-surgery preoperative blood pressures are associated with postoperative adverse events. Methods We conducted a retrospective, observational study of adult patients having elective […]
Read MoreAuthors: Muñoz-Leija D et al Cureus 16(3): e56567. doi:10.7759/cureus.56567 Abstract Introduction: Lumbar puncture (LP) is a common invasive technique considered an essential learning milestone for anesthesiologists due to its application in spinal anesthesia. We aimed to develop an in-house LP simulator, test its effectiveness in learning the steps to perform an LP and analyze its impact on […]
Read MoreAuthors: Chatterjee P et al Cureus 15(4): e37995. doi:10.7759/cureus.37995 Abstract Postpartum hemorrhage (PPH) is among the leading causes of maternal morbidity and mortality, and various blood conservation strategies can be implemented to minimize blood loss. Acute normovolemic hemodilution (ANH) is a simple yet effective blood management tool in the armamentarium of an anesthesiologist, the use […]
Read MoreAuthors: Simon J Davies, FRCA, MD et al Anesthesiology April 2024. Background The Hypotension Prediction Index (the index) software is a machine learning algorithm that detects physiological changes that may lead to hypotension. The original validation used a case control (backwards) analysis that has been suggested to be biased. We therefore conducted a cohort (forwards) […]
Read MoreAuthors: Marijn P. Mulder, M.Sc. et al Anesthesiology April 2024. Background The Hypotension Prediction Index is designed to timely predict intraoperative hypotension and is based on arterial waveform analysis using machine learning. It has recently been suggested that this algorithm is highly correlated with the mean arterial pressure (MAP) itself. Therefore, the aim of this […]
Read MoreAUTHORS: Warner, Matthew A. MD et al Anesthesia & Analgesia 138(4):p 728-737, April BACKGROUND: Preoperative anemia is associated with adverse outcomes in cardiac surgery, yet it remains unclear what proportion of this association is mediated through red blood cell (RBC) transfusions. METHODS: This is a historical observational cohort study of adults undergoing coronary artery bypass grafting […]
Read MoreAuthor: Singam A Cureus 16(2): e55021. doi:10.7759/cureus.55021 Abstract Myocardial injury in the context of septic shock presents a multifaceted challenge in critical care medicine with implications for patient prognosis and therapeutic strategies. This comprehensive review explores the mechanisms, diagnostic approaches, and clinical implications of myocardial injury as a harbinger of multi-organ failure in septic shock. […]
Read MoreAuthors: Alanzi A K, et al Cureus 15(4): e37351. doi:10.7759/cureus.37351 Abstract An abdominal aortic aneurysm (AAA) is a disease characterized by an abnormal bulge or swelling in the aorta. It could be serious if left unobserved, and with time, it swells and eventually ruptures, resulting in massive bleeding inside, and, more likely, causes death. This […]
Read MoreAuthors: Yukiko Yamazaki, M.D. Koji Hosokawa, M.D., Ph.D. Anesthesiology April 2024. To the Editor: We read with great interest the recent article by Xu et al. that discusses how the Swallowing, Tongue protrusion, Airway protection reflected by spontaneous and suctioning cough, and Glasgow coma scale Evaluation (STAGE) score of neurologic patients may predict the success of extubation. However, […]
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