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AUTHORS: Meng, Marie-Louise MD et al Anesthesia & Analgesia May 16, 2023. BACKGROUND: Patients with pulmonary hypertension have a high risk of maternal morbidity and mortality. It is unknown if a trial of labor carries a lower risk of morbidity in these patients compared to a planned cesarean delivery. The objective of this study was […]
Read MoreAUTHORS: Haller G et al European Journal of Anaesthesiology 34(8):p 492-507, August 2017. BACKGROUND Limited information exists about the epidemiology and outcome of surgical patients at increased risk of postoperative pulmonary complications (PPCs), and how intraoperative ventilation was managed in these patients. OBJECTIVES To determine the incidence of surgical patients at increased risk of PPCs, and […]
Read MoreAUTHORS: Chen, Zhao-Rong MM et al Anesthesia & Analgesia 137(2):p 426-439, August 2023. BACKGROUND: Myocardial infarction is a common perioperative complication, and blood flow restoration causes ischemia/reperfusion injury (IRI). Dexmedetomidine (DEX) pretreatment can protect against cardiac IRI, but the mechanism is still insufficiently understood. METHODS: In vivo, myocardial ischemia/reperfusion (30 minutes/120 minutes) was induced via ligation […]
Read MoreAUTHORS: Hansen, Elizabeth E. MD, PhD et al Anesthesia & Analgesia 137(1):p 98-107, July 2023. BACKGROUND: Children are particularly vulnerable to adverse health outcomes related to climate change. Inhalational anesthetics are potent greenhouse gasses (GHGs) and contribute significantly to health care–generated emissions. Desflurane and nitrous oxide have very high global warming potentials. Eliminating their use, as […]
Read MoreAUTHORS: Thilen, Stephan R. MD, MS et al Anesthesia & Analgesia May 12, 2023. BACKGROUND: The optimal pharmacological reversal strategy for neuromuscular blockade remains undefined even in the setting of strong recommendations for quantitative neuromuscular monitoring by several national and international anesthesiology societies. We evaluated a protocol for managing rocuronium blockade and reversal, using quantitative […]
Read MoreAUTHORS: Theroux, Mary C. MD et al Anesthesia & Analgesia 137(5):p 1075-1083, November 2023. BACKGROUND: Recently, tracheal narrowing has been recognized as a significant comorbid condition in patients with Morquio A, also known as mucopolysaccharidosis IVA. We studied a large cohort of patients with Morquio A to describe the extent of their tracheal narrowing and its […]
Read MoreAUTHORS: Zhang, Luming MD, PhD et al Anesthesia & Analgesia 137(4):p 850-858, October 2023. BACKGROUND: Previous studies on the association between the timing of corticosteroid administration and mortality in septic shock focused only on short-term mortality and produced conflicting results. We performed a retrospective review of a large administrative database of intensive care unit (ICU) patients […]
Read MoreAUTHORS: Cadd, Matthew MRCP et al Anesthesia & Analgesia May 11, 2023. BACKGROUND: Pruritus is a frequently reported and unpleasant side effect following intrathecal opioid use with frequency further increased among parturients. We have performed a systematic review to assess the overall efficacy of ondansetron for the prevention of pruritus in patients receiving intrathecal opioid […]
Read MoreAUTHORS: Guo, Xingzhi MD, PhD et al Anesthesia & Analgesia 137(4):p 896-905, October 2023. BACKGROUND: Observational studies have suggested an intricate relationship among chronic pain (CP), use of analgesics, and cognitive status, but it remains unclear whether these associations are of a causal nature. METHODS: To investigate the causal relationship among them, summary statistics of 9 […]
Read MoreAUTHORS: Ma, Yulong MD, PhD et al Anesthesia & Analgesia May 04, 2023. BACKGROUND: In the past 20 years, anesthesiology has become one of the most advanced specialties and has undergone rapid development. However, public awareness regarding anesthesiology and anesthesiologists is limited, especially in developing countries. It is important for anesthesiologists to make the public […]
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